Optimization of Extract Method for Cynomorium songaricum Rupr. by Response Surface Methodology
The present study aimed to evaluate the quality of Cynomorium songaricum Rupr. from different producing areas, which is an edible, holoparasitic, and desert plant that has been used in traditional medicine for improving immunity and kidney function and treating constipation. We optimized the extract...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Analytical Methods in Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2017/6153802 |
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| author | Xiang Zhang Caimei Gu Bashir Ahmad Linfang Huang |
| author_facet | Xiang Zhang Caimei Gu Bashir Ahmad Linfang Huang |
| author_sort | Xiang Zhang |
| collection | DOAJ |
| description | The present study aimed to evaluate the quality of Cynomorium songaricum Rupr. from different producing areas, which is an edible, holoparasitic, and desert plant that has been used in traditional medicine for improving immunity and kidney function and treating constipation. We optimized the extract conditions by response surface methodology (RSM) and determined the content of gallic acid, protocatechuic acid, and catechin of C. songaricum simultaneously from different producing areas by high-performance liquid chromatography (HPLC). It is the first study in which the RSM was used to optimize the extract condition of C. songaricum with multiple evaluation factors, ensuring the efficiency and accuracy of the study. The results were analyzed by principal component analysis, and they showed that the quality of C. songaricum from Qinghai Province was the best, while the quality of C. songaricum from Gansu Province was the worst. For the first time, the two ecotypes of C. songaricum, including Outside Great Wall type and Inside Great Wall type, were discovered and identified by the chemical marker protocatechuic acid. This study is the scientific basis for quality evaluation, especially for food safety. |
| format | Article |
| id | doaj-art-deb6239660cf4c2196877e7646050fea |
| institution | OA Journals |
| issn | 2090-8865 2090-8873 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Analytical Methods in Chemistry |
| spelling | doaj-art-deb6239660cf4c2196877e7646050fea2025-08-20T02:21:21ZengWileyJournal of Analytical Methods in Chemistry2090-88652090-88732017-01-01201710.1155/2017/61538026153802Optimization of Extract Method for Cynomorium songaricum Rupr. by Response Surface MethodologyXiang Zhang0Caimei Gu1Bashir Ahmad2Linfang Huang3Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences (CAMS), Peking Union Medical College (PUMC), Beijing 100193, ChinaInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences (CAMS), Peking Union Medical College (PUMC), Beijing 100193, ChinaCentre for Biotechnology and Microbiology, University of Peshawar, Peshawar, PakistanInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences (CAMS), Peking Union Medical College (PUMC), Beijing 100193, ChinaThe present study aimed to evaluate the quality of Cynomorium songaricum Rupr. from different producing areas, which is an edible, holoparasitic, and desert plant that has been used in traditional medicine for improving immunity and kidney function and treating constipation. We optimized the extract conditions by response surface methodology (RSM) and determined the content of gallic acid, protocatechuic acid, and catechin of C. songaricum simultaneously from different producing areas by high-performance liquid chromatography (HPLC). It is the first study in which the RSM was used to optimize the extract condition of C. songaricum with multiple evaluation factors, ensuring the efficiency and accuracy of the study. The results were analyzed by principal component analysis, and they showed that the quality of C. songaricum from Qinghai Province was the best, while the quality of C. songaricum from Gansu Province was the worst. For the first time, the two ecotypes of C. songaricum, including Outside Great Wall type and Inside Great Wall type, were discovered and identified by the chemical marker protocatechuic acid. This study is the scientific basis for quality evaluation, especially for food safety.http://dx.doi.org/10.1155/2017/6153802 |
| spellingShingle | Xiang Zhang Caimei Gu Bashir Ahmad Linfang Huang Optimization of Extract Method for Cynomorium songaricum Rupr. by Response Surface Methodology Journal of Analytical Methods in Chemistry |
| title | Optimization of Extract Method for Cynomorium songaricum Rupr. by Response Surface Methodology |
| title_full | Optimization of Extract Method for Cynomorium songaricum Rupr. by Response Surface Methodology |
| title_fullStr | Optimization of Extract Method for Cynomorium songaricum Rupr. by Response Surface Methodology |
| title_full_unstemmed | Optimization of Extract Method for Cynomorium songaricum Rupr. by Response Surface Methodology |
| title_short | Optimization of Extract Method for Cynomorium songaricum Rupr. by Response Surface Methodology |
| title_sort | optimization of extract method for cynomorium songaricum rupr by response surface methodology |
| url | http://dx.doi.org/10.1155/2017/6153802 |
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