Derivation and external validation of a risk score for predicting HIV-associated tuberculosis to support case finding and preventive therapy scale-up: A cohort study.

Derivation and external validation of a risk score for predicting HIV-associated tuberculosis to support case finding and preventive therapy scale-up: A cohort study.

<h4>Background</h4>Among people living with HIV (PLHIV), more flexible and sensitive tuberculosis (TB) screening tools capable of detecting both symptomatic and subclinical active TB are needed to (1) reduce morbidity and mortality from undiagnosed TB; (2) facilitate scale-up of tubercul...

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Main Authors: Andrew F Auld, Andrew D Kerkhoff, Yasmeen Hanifa, Robin Wood, Salome Charalambous, Yuliang Liu, Tefera Agizew, Anikie Mathoma, Rosanna Boyd, Anand Date, Ray W Shiraishi, George Bicego, Unami Mathebula-Modongo, Heather Alexander, Christopher Serumola, Goabaone Rankgoane-Pono, Pontsho Pono, Alyssa Finlay, James C Shepherd, Tedd V Ellerbrock, Alison D Grant, Katherine Fielding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-09-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1003739
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