Study of Erythropoietin and number of antibiotics in renal failure and thalassemia patients

The current study included 130 people over a period of research from October 2015 to May 2016 who have renal failure and thalassemia. Samples were studied divided in three groups: the first group: included 50 people (62-20 years) with renal failure, and the second group: included 50 people(30-12 ye...

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Main Authors: Ansam Hussein Ali, Sahib J. Abdurahman, Mousa J. Mohammed
Format: Article
Language:English
Published: Tikrit University 2023-02-01
Series:Tikrit Journal of Pure Science
Subjects:
Online Access:https://tjpsj.org/index.php/tjps/article/view/853
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author Ansam Hussein Ali
Sahib J. Abdurahman
Mousa J. Mohammed
author_facet Ansam Hussein Ali
Sahib J. Abdurahman
Mousa J. Mohammed
author_sort Ansam Hussein Ali
collection DOAJ
description The current study included 130 people over a period of research from October 2015 to May 2016 who have renal failure and thalassemia. Samples were studied divided in three groups: the first group: included 50 people (62-20 years) with renal failure, and the second group: included 50 people(30-12 years) infected with thalassemia in addition to the 30 people (18-54 years) represented a group of healthy control. The present study aimed to find out the dynamic effect of the hormone erythropoietin and its role in anemia by examining the level of serum hormone erythropoietin among patients with thalassemia as well as anemia in patients with renal failure, in addition to the effect of some of the biochemical parameters associated antioxidants system such as Glutathione (GSH), superoxide dismutase (SOD) and catalase. The study concludes the following results: The results showed a significant decrease (P≤0.01) in the concentration of the erythropoietin hormone in the two groups of patients renal failure  while there was a significant increase in patients with a group of thalassemia for males and did not record results significant difference for a group of female thalassemia patients when compared with the control group. The results show that there is a significant decrease in the level of glutathione and SOD and catalase enzyme, and for both males and females in the patients groups when compared with the control group
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spelling doaj-art-deb1ac80cdbb4cc694c780571a7cf8a22025-08-20T03:17:47ZengTikrit UniversityTikrit Journal of Pure Science1813-16622415-17262023-02-0122810.25130/tjps.v22i8.853Study of Erythropoietin and number of antibiotics in renal failure and thalassemia patientsAnsam Hussein AliSahib J. AbdurahmanMousa J. Mohammed The current study included 130 people over a period of research from October 2015 to May 2016 who have renal failure and thalassemia. Samples were studied divided in three groups: the first group: included 50 people (62-20 years) with renal failure, and the second group: included 50 people(30-12 years) infected with thalassemia in addition to the 30 people (18-54 years) represented a group of healthy control. The present study aimed to find out the dynamic effect of the hormone erythropoietin and its role in anemia by examining the level of serum hormone erythropoietin among patients with thalassemia as well as anemia in patients with renal failure, in addition to the effect of some of the biochemical parameters associated antioxidants system such as Glutathione (GSH), superoxide dismutase (SOD) and catalase. The study concludes the following results: The results showed a significant decrease (P≤0.01) in the concentration of the erythropoietin hormone in the two groups of patients renal failure  while there was a significant increase in patients with a group of thalassemia for males and did not record results significant difference for a group of female thalassemia patients when compared with the control group. The results show that there is a significant decrease in the level of glutathione and SOD and catalase enzyme, and for both males and females in the patients groups when compared with the control group https://tjpsj.org/index.php/tjps/article/view/853Erythropoietinantibioticsthalassemia patients
spellingShingle Ansam Hussein Ali
Sahib J. Abdurahman
Mousa J. Mohammed
Study of Erythropoietin and number of antibiotics in renal failure and thalassemia patients
Tikrit Journal of Pure Science
Erythropoietin
antibiotics
thalassemia patients
title Study of Erythropoietin and number of antibiotics in renal failure and thalassemia patients
title_full Study of Erythropoietin and number of antibiotics in renal failure and thalassemia patients
title_fullStr Study of Erythropoietin and number of antibiotics in renal failure and thalassemia patients
title_full_unstemmed Study of Erythropoietin and number of antibiotics in renal failure and thalassemia patients
title_short Study of Erythropoietin and number of antibiotics in renal failure and thalassemia patients
title_sort study of erythropoietin and number of antibiotics in renal failure and thalassemia patients
topic Erythropoietin
antibiotics
thalassemia patients
url https://tjpsj.org/index.php/tjps/article/view/853
work_keys_str_mv AT ansamhusseinali studyoferythropoietinandnumberofantibioticsinrenalfailureandthalassemiapatients
AT sahibjabdurahman studyoferythropoietinandnumberofantibioticsinrenalfailureandthalassemiapatients
AT mousajmohammed studyoferythropoietinandnumberofantibioticsinrenalfailureandthalassemiapatients