Metagenomic sequencing of mpox virus clade Ib lesions identifies possible bacterial and viral co-infections in hospitalized patients in eastern DRC

Metagenomic sequencing of mpox virus clade Ib lesions identifies possible bacterial and viral co-infections in hospitalized patients in eastern DRC

ABSTRACT Mpox is an emerging zoonotic disease that caused two public health emergencies of international concern within two years. Less is known about the interplay of microbial organisms in mpox lesions which could result in superinfections that exacerbate outcomes or delay recovery. We utilized a...

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Main Authors: Leonard Schuele, Leandre Murhula Masirika, Hayley Cassidy, Philip T. L. C. Clausen, Luca M. Zaeck, Marjan Boter, Pacifique Ndishimye, Jean Claude Udahemuka, Rory D. de Vries, Saria Otani, Richard Molenkamp, David F. Nieuwenhuijse, Justin Bengehya Mbiribindi, Freddy Belesi Siangoli, Marion Koopmans, Frank M. Aarestrup, Bas B. Oude Munnink
Format: Article
Language:English
Published: American Society for Microbiology 2025-07-01
Series:Microbiology Spectrum
Subjects:
mpox
mpox virus
clade Ib
metagenomics
antimicrobial resistance
co-infections
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00512-25
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