Intravascular Papillary Endothelial Hyperplasia of Buccal Mucosa Masquerading as Mucocele - A Case Report

Introduction: Oral intravascular papillary endothelial hyperplasia (IPEH) is a rare entity with only 105 cases reported so far. Labial and buccal mucosa are the commonly affected sites. These sites are coincidently subjected to continuous minor trauma, which led the researchers to opine that IPEH co...

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Main Authors: Deepak Pandiar, Reshma Poothakulath Krishnan, Aklesha Behera, Pratibha Ramani
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-10-01
Series:Indian Journal of Dental Research
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Online Access:https://journals.lww.com/10.4103/ijdr.ijdr_258_22
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author Deepak Pandiar
Reshma Poothakulath Krishnan
Aklesha Behera
Pratibha Ramani
author_facet Deepak Pandiar
Reshma Poothakulath Krishnan
Aklesha Behera
Pratibha Ramani
author_sort Deepak Pandiar
collection DOAJ
description Introduction: Oral intravascular papillary endothelial hyperplasia (IPEH) is a rare entity with only 105 cases reported so far. Labial and buccal mucosa are the commonly affected sites. These sites are coincidently subjected to continuous minor trauma, which led the researchers to opine that IPEH could have a traumatic etiology with a further role of fibroblast growth factors. Clinical Presentation: We report a case of IPEH of right buccal mucosa in a 35 years old South Indian male who clinically presented as mucocele. Histopathologically, multiple lesions were found. Immunohistochemical and histochemical findings have also been presented. Discussion: The case is supported by a plausible mechanism involved in the pathogenesis. Thus, IPEH must be included in the clinical differential diagnosis of oral mucoceles and hemangioma. Take-away Lessons: Being a reactive lesion, it does not require extensive treatment. Clinicians and histopathologists must be aware of this uncommon yet benign condition for appropriate therapy.
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institution Kabale University
issn 0970-9290
1998-3603
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publishDate 2023-10-01
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spelling doaj-art-dea1ee640b2e4810b1cc772e692443202025-02-07T15:32:12ZengWolters Kluwer Medknow PublicationsIndian Journal of Dental Research0970-92901998-36032023-10-0134444544710.4103/ijdr.ijdr_258_22Intravascular Papillary Endothelial Hyperplasia of Buccal Mucosa Masquerading as Mucocele - A Case ReportDeepak PandiarReshma Poothakulath KrishnanAklesha BeheraPratibha RamaniIntroduction: Oral intravascular papillary endothelial hyperplasia (IPEH) is a rare entity with only 105 cases reported so far. Labial and buccal mucosa are the commonly affected sites. These sites are coincidently subjected to continuous minor trauma, which led the researchers to opine that IPEH could have a traumatic etiology with a further role of fibroblast growth factors. Clinical Presentation: We report a case of IPEH of right buccal mucosa in a 35 years old South Indian male who clinically presented as mucocele. Histopathologically, multiple lesions were found. Immunohistochemical and histochemical findings have also been presented. Discussion: The case is supported by a plausible mechanism involved in the pathogenesis. Thus, IPEH must be included in the clinical differential diagnosis of oral mucoceles and hemangioma. Take-away Lessons: Being a reactive lesion, it does not require extensive treatment. Clinicians and histopathologists must be aware of this uncommon yet benign condition for appropriate therapy.https://journals.lww.com/10.4103/ijdr.ijdr_258_22bfgfcovid-19intravascular papillary endothelial hyperplasiatrauma
spellingShingle Deepak Pandiar
Reshma Poothakulath Krishnan
Aklesha Behera
Pratibha Ramani
Intravascular Papillary Endothelial Hyperplasia of Buccal Mucosa Masquerading as Mucocele - A Case Report
Indian Journal of Dental Research
bfgf
covid-19
intravascular papillary endothelial hyperplasia
trauma
title Intravascular Papillary Endothelial Hyperplasia of Buccal Mucosa Masquerading as Mucocele - A Case Report
title_full Intravascular Papillary Endothelial Hyperplasia of Buccal Mucosa Masquerading as Mucocele - A Case Report
title_fullStr Intravascular Papillary Endothelial Hyperplasia of Buccal Mucosa Masquerading as Mucocele - A Case Report
title_full_unstemmed Intravascular Papillary Endothelial Hyperplasia of Buccal Mucosa Masquerading as Mucocele - A Case Report
title_short Intravascular Papillary Endothelial Hyperplasia of Buccal Mucosa Masquerading as Mucocele - A Case Report
title_sort intravascular papillary endothelial hyperplasia of buccal mucosa masquerading as mucocele a case report
topic bfgf
covid-19
intravascular papillary endothelial hyperplasia
trauma
url https://journals.lww.com/10.4103/ijdr.ijdr_258_22
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