Fire needle pretreatment combined with ALA-PDT for Penile Bowen's disease: A case report

Bowen's disease (BD), squamous cell carcinoma (SCC) in situ, presents treatment challenges when located on the penis. Primarily concerning potential scarring and functional impairment following standard surgical excision (e.g., Mohs micrographic surgery). Aminolevulinic acid photodynamic therap...

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Bibliographic Details
Main Authors: Tianming Ma, Xiaoqing Xiang, Yanliang Li, Runqun Liu, Yunyun Cao
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Photodiagnosis and Photodynamic Therapy
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Online Access:http://www.sciencedirect.com/science/article/pii/S1572100025001632
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Summary:Bowen's disease (BD), squamous cell carcinoma (SCC) in situ, presents treatment challenges when located on the penis. Primarily concerning potential scarring and functional impairment following standard surgical excision (e.g., Mohs micrographic surgery). Aminolevulinic acid photodynamic therapy (ALA-PDT) may provide a valuable alternative, especially for this sensitive anatomical site. This report describes the successful treatment of a case of penile BD using fire needle pretreatment immediately preceding ALA-PDT. The patient achieved complete clinical and histological remission and remained disease-free at 2 years of follow-up.
ISSN:1572-1000