The Interplay Between Melatonin and Nitric Oxide: Mechanisms and Implications in Stroke Pathophysiology

The Interplay Between Melatonin and Nitric Oxide: Mechanisms and Implications in Stroke Pathophysiology

This work reviews the complex interplay between melatonin and nitric oxide (NO) in the central nervous system (CNS), with a detailed focus on its involvement in stroke pathophysiology. Melatonin, a neurohormone with potent antioxidant, anti-inflammatory, and neuroprotective properties, and NO, a gas...

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Bibliographic Details
Main Authors: Santos Blanco, María del Mar Muñoz-Gallardo, Raquel Hernández, María Ángeles Peinado
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Antioxidants
Subjects:
melatonin
nitric oxide
stroke
CNS
ischemia
molecular mechanisms
Online Access:https://www.mdpi.com/2076-3921/14/6/724
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