Prognosis of Pregnancies with Different Degrees of Glucose Intolerance

OBJECTIVE: The purpose of the present study was to evaluate the effect of different degrees of glucose intolerance on maternal and perinatal outcomes. STUDY DESIGN: Retrospective data of 500 singleton pregnancies screened for gestational diabetes mellitus were reviewed. Maternal and perinatal outco...

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Main Authors: Sevgi Ayhan, Sündüz Özlem Altınkaya, Tayfun Güngör, Utku Özcan
Format: Article
Language:English
Published: Medical Network 2013-08-01
Series:Gynecology Obstetrics & Reproductive Medicine
Subjects:
Online Access:https://gorm.com.tr/index.php/GORM/article/view/190
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author Sevgi Ayhan
Sündüz Özlem Altınkaya
Tayfun Güngör
Utku Özcan
author_facet Sevgi Ayhan
Sündüz Özlem Altınkaya
Tayfun Güngör
Utku Özcan
author_sort Sevgi Ayhan
collection DOAJ
description OBJECTIVE: The purpose of the present study was to evaluate the effect of different degrees of glucose intolerance on maternal and perinatal outcomes. STUDY DESIGN: Retrospective data of 500 singleton pregnancies screened for gestational diabetes mellitus were reviewed. Maternal and perinatal outcomes for four different groups were compared. First group consisted of patients with normal 50-g test, second group was formed by patients with abnormal 50-g test but a normal 100-g test. Third group included patients with one abnormal value after 100-g test. Patients in the fourth group were diagnosed to have gestational diabetes mellitus with two or more abnormal values after 100-g test. RESULTS: Macrosomia, neonatal intensive care unit admission and preterm premature rupture of membranes were the highest in the group with one elevated value after glucose tolerance test. Preterm labor was the highest in the gestational diabetes group. The difference in the rate of preeclampsia, polyhydramnios, neonatal hypoglycemia and hypocalcemia was not statistically significant (p>0.05). CONCLUSION: Although women with one elevated value after glucose tolerance test are not diagnosed with gestational diabetes mellitus, they are still at risk for adverse maternal and perinatal outcomes. They seem to be prone to develop obstetric complications related to glucose intolerance and should be followed up carefully during the antepartum and intrapartum period.
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institution Kabale University
issn 1300-4751
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publishDate 2013-08-01
publisher Medical Network
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series Gynecology Obstetrics & Reproductive Medicine
spelling doaj-art-de7a2344bec243f3b3cee6f8898176892025-02-11T21:20:47ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182013-08-01192129Prognosis of Pregnancies with Different Degrees of Glucose IntoleranceSevgi Ayhan0Sündüz Özlem Altınkaya1Tayfun Güngör2Utku Özcan3Department of Gynecology & Obstetrics, Dr. Zekai Tahir Burak Women's Health Research and Education Hospital, AnkaraDepartment of Gynecology & Obstetrics, Adnan Menderes University Faculty of Medicine, AydınDepartment of Gynecology & Obstetrics, Dr. Zekai Tahir Burak aWomen's Health Research and Education Hospital, AnkaraDepartment of Gynecology & Obstetrics, Dr. Zekai Tahir Burak aWomen's Health Research and Education Hospital, Ankara OBJECTIVE: The purpose of the present study was to evaluate the effect of different degrees of glucose intolerance on maternal and perinatal outcomes. STUDY DESIGN: Retrospective data of 500 singleton pregnancies screened for gestational diabetes mellitus were reviewed. Maternal and perinatal outcomes for four different groups were compared. First group consisted of patients with normal 50-g test, second group was formed by patients with abnormal 50-g test but a normal 100-g test. Third group included patients with one abnormal value after 100-g test. Patients in the fourth group were diagnosed to have gestational diabetes mellitus with two or more abnormal values after 100-g test. RESULTS: Macrosomia, neonatal intensive care unit admission and preterm premature rupture of membranes were the highest in the group with one elevated value after glucose tolerance test. Preterm labor was the highest in the gestational diabetes group. The difference in the rate of preeclampsia, polyhydramnios, neonatal hypoglycemia and hypocalcemia was not statistically significant (p>0.05). CONCLUSION: Although women with one elevated value after glucose tolerance test are not diagnosed with gestational diabetes mellitus, they are still at risk for adverse maternal and perinatal outcomes. They seem to be prone to develop obstetric complications related to glucose intolerance and should be followed up carefully during the antepartum and intrapartum period. https://gorm.com.tr/index.php/GORM/article/view/190Glucose intolerancePregnancyGestational diabetesPerinatal outcome
spellingShingle Sevgi Ayhan
Sündüz Özlem Altınkaya
Tayfun Güngör
Utku Özcan
Prognosis of Pregnancies with Different Degrees of Glucose Intolerance
Gynecology Obstetrics & Reproductive Medicine
Glucose intolerance
Pregnancy
Gestational diabetes
Perinatal outcome
title Prognosis of Pregnancies with Different Degrees of Glucose Intolerance
title_full Prognosis of Pregnancies with Different Degrees of Glucose Intolerance
title_fullStr Prognosis of Pregnancies with Different Degrees of Glucose Intolerance
title_full_unstemmed Prognosis of Pregnancies with Different Degrees of Glucose Intolerance
title_short Prognosis of Pregnancies with Different Degrees of Glucose Intolerance
title_sort prognosis of pregnancies with different degrees of glucose intolerance
topic Glucose intolerance
Pregnancy
Gestational diabetes
Perinatal outcome
url https://gorm.com.tr/index.php/GORM/article/view/190
work_keys_str_mv AT sevgiayhan prognosisofpregnancieswithdifferentdegreesofglucoseintolerance
AT sunduzozlemaltınkaya prognosisofpregnancieswithdifferentdegreesofglucoseintolerance
AT tayfungungor prognosisofpregnancieswithdifferentdegreesofglucoseintolerance
AT utkuozcan prognosisofpregnancieswithdifferentdegreesofglucoseintolerance