Resolution of Combined Hamartoma of Retina And Retinal Pigment Epithelium (CHRRPE) with Following Pars Plana Vitrectomy
Combined hamartoma of retina and retinal pigment epithelium (CHRRPE) is a benign tumor located at the posterior pole. The pathogenesis of the lesion is unknown however some authors propose that the tumor may arise from undifferentiated ectopic progenitor cells which were otherwise destined for RPE a...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2021-07-01
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| Series: | Delhi Journal of Ophthalmology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.7869/djo.695 |
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| Summary: | Combined hamartoma of retina and retinal pigment epithelium (CHRRPE) is a benign tumor located at the posterior pole. The pathogenesis of the lesion is unknown however some authors propose that the tumor may arise from undifferentiated ectopic progenitor cells which were otherwise destined for RPE and demonstrate failure to completely differentiate. These cells then undergo hyperplasia and accumulate in the neurosensory retina. Optical coherence tomography (OCT) assists in classification of the lesions based on location and differentiates from an epiretinal membrane (ERM). Surgical intervention is warranted in cases that produce macular distortion with/without associated ERM or retinal detachment and those producing visual complaints. Similar was the case with a 26-year-old male who presented with unilateral metamorphopsia that was attributed to CHRRPE with a grade two ERM. Pars plana vitrectomy with ERM peeling resulted in resolution of disabling symptoms and anatomical success as visible on OCT. |
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| ISSN: | 0972-0200 2454-2784 |