Predictors of macrovascular complications in Al-Madinah Al-Munawara type 2 diabetes mellitus patients, Saudi Arabia: A cross-sectional study

Background/aim Diabetes mellitus is a metabolic disease characterized by chronic hyperglycemia, which causes macrovascular complications that account for most of the morbidity, hospitalizations, and deaths. The goal of this study is to evaluate the relationship between macrovascular complications an...

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Main Authors: Inas R. El-Alameey, Abeer A. Al-Mutairi, Rama D. Alamri, Raoum S. Saed, Rema A. Alqubali, Ghada A. Al-Abdudullatif, Shrouq R. Al-Harbi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Journal of the Arab Society for Medical Research
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Online Access:https://journals.lww.com/10.4103/jasmr.jasmr_23_23
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author Inas R. El-Alameey
Abeer A. Al-Mutairi
Rama D. Alamri
Raoum S. Saed
Rema A. Alqubali
Ghada A. Al-Abdudullatif
Shrouq R. Al-Harbi
author_facet Inas R. El-Alameey
Abeer A. Al-Mutairi
Rama D. Alamri
Raoum S. Saed
Rema A. Alqubali
Ghada A. Al-Abdudullatif
Shrouq R. Al-Harbi
author_sort Inas R. El-Alameey
collection DOAJ
description Background/aim Diabetes mellitus is a metabolic disease characterized by chronic hyperglycemia, which causes macrovascular complications that account for most of the morbidity, hospitalizations, and deaths. The goal of this study is to evaluate the relationship between macrovascular complications and associated risk factors in Al-Madinah Al-Munawara patients suffering from type 2 diabetes mellitus. Patients and methods This descriptive cross-sectional study involved 275 type 2 diabetes mellitus patients who resided in Al-Madinah Al-Munawara and visited the diabetic clinic at King Fahd Hospital on a regular basis. Participants in the study ranged in age from 20 to 65. Hemoglobin, glycated hemoglobin, serum calcium, fasting blood glucose, and lipid profile were analyzed. Results Out of 275 patients with type 2 diabetes mellitus, 113 have had macrovascular complications. A significant association (P<0.05) has been observed between the age of the patients and different forms of macrovascular complications, which impact 62.7% of the elderly (41–65 years old). The prevalence of macrovascular complications was higher among females. Glycated hemoglobin levels positively correlated with the number of hospitalizations, high blood pressure, hemoglobin, and serum cholesterol levels. Macrovascular complications are positively correlated with age, sex, hypertension, and therapy type (P<0.05), while physical activity has a negative significant effect on the appearance of macrovascular complications by multiple regression analysis. Conclusion In this study, diabetic macrovascular complications were prevalent. The age, sex of participants, and type of treatment were independent predictors of macrovascular complications. Hypertension has a significant positive effect on the appearance of macrovascular complications. Physically inactive patients have a higher risk of macrovascular complications.
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spelling doaj-art-de6bd6e83d584baa838b7da3ce9f4a412025-08-20T02:50:48ZengWolters Kluwer Medknow PublicationsJournal of the Arab Society for Medical Research1687-42932024-01-01191556210.4103/jasmr.jasmr_23_23Predictors of macrovascular complications in Al-Madinah Al-Munawara type 2 diabetes mellitus patients, Saudi Arabia: A cross-sectional studyInas R. El-AlameeyAbeer A. Al-MutairiRama D. AlamriRaoum S. SaedRema A. AlqubaliGhada A. Al-AbdudullatifShrouq R. Al-HarbiBackground/aim Diabetes mellitus is a metabolic disease characterized by chronic hyperglycemia, which causes macrovascular complications that account for most of the morbidity, hospitalizations, and deaths. The goal of this study is to evaluate the relationship between macrovascular complications and associated risk factors in Al-Madinah Al-Munawara patients suffering from type 2 diabetes mellitus. Patients and methods This descriptive cross-sectional study involved 275 type 2 diabetes mellitus patients who resided in Al-Madinah Al-Munawara and visited the diabetic clinic at King Fahd Hospital on a regular basis. Participants in the study ranged in age from 20 to 65. Hemoglobin, glycated hemoglobin, serum calcium, fasting blood glucose, and lipid profile were analyzed. Results Out of 275 patients with type 2 diabetes mellitus, 113 have had macrovascular complications. A significant association (P<0.05) has been observed between the age of the patients and different forms of macrovascular complications, which impact 62.7% of the elderly (41–65 years old). The prevalence of macrovascular complications was higher among females. Glycated hemoglobin levels positively correlated with the number of hospitalizations, high blood pressure, hemoglobin, and serum cholesterol levels. Macrovascular complications are positively correlated with age, sex, hypertension, and therapy type (P<0.05), while physical activity has a negative significant effect on the appearance of macrovascular complications by multiple regression analysis. Conclusion In this study, diabetic macrovascular complications were prevalent. The age, sex of participants, and type of treatment were independent predictors of macrovascular complications. Hypertension has a significant positive effect on the appearance of macrovascular complications. Physically inactive patients have a higher risk of macrovascular complications.https://journals.lww.com/10.4103/jasmr.jasmr_23_23al-madinah al-munawaramacrovascular complicationstype 2 diabetes mellitus
spellingShingle Inas R. El-Alameey
Abeer A. Al-Mutairi
Rama D. Alamri
Raoum S. Saed
Rema A. Alqubali
Ghada A. Al-Abdudullatif
Shrouq R. Al-Harbi
Predictors of macrovascular complications in Al-Madinah Al-Munawara type 2 diabetes mellitus patients, Saudi Arabia: A cross-sectional study
Journal of the Arab Society for Medical Research
al-madinah al-munawara
macrovascular complications
type 2 diabetes mellitus
title Predictors of macrovascular complications in Al-Madinah Al-Munawara type 2 diabetes mellitus patients, Saudi Arabia: A cross-sectional study
title_full Predictors of macrovascular complications in Al-Madinah Al-Munawara type 2 diabetes mellitus patients, Saudi Arabia: A cross-sectional study
title_fullStr Predictors of macrovascular complications in Al-Madinah Al-Munawara type 2 diabetes mellitus patients, Saudi Arabia: A cross-sectional study
title_full_unstemmed Predictors of macrovascular complications in Al-Madinah Al-Munawara type 2 diabetes mellitus patients, Saudi Arabia: A cross-sectional study
title_short Predictors of macrovascular complications in Al-Madinah Al-Munawara type 2 diabetes mellitus patients, Saudi Arabia: A cross-sectional study
title_sort predictors of macrovascular complications in al madinah al munawara type 2 diabetes mellitus patients saudi arabia a cross sectional study
topic al-madinah al-munawara
macrovascular complications
type 2 diabetes mellitus
url https://journals.lww.com/10.4103/jasmr.jasmr_23_23
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