OXA-48-producing Enterobacteriaceae in North of Morocco: Data from regional hospital of Tangier
Introduction: This is a three-year retro-prospective study aimed at assessing the prevalence of carbapenem-resistant Enterobacteriaceae and to study three-year retrospective study aimed at determining the prevalence of carbapenem-resistant Enterobacteriaceae and analyzing the characteristics of OXA...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
The Journal of Infection in Developing Countries
2025-01-01
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| Series: | Journal of Infection in Developing Countries |
| Subjects: | |
| Online Access: | https://jidc.org/index.php/journal/article/view/18564 |
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| Summary: | Introduction: This is a three-year retro-prospective study aimed at assessing the prevalence of carbapenem-resistant Enterobacteriaceae and to study three-year retrospective study aimed at determining the prevalence of carbapenem-resistant Enterobacteriaceae and analyzing the characteristics of OXA-48 producers.
Methodology: Six thousand one hundred eighteen bacteriological samples were assessed at Mohamed V Regional Hospital microbiology laboratory in Tangier, Morocco.
Results: Of the 1,228 identified Enterobacteriaceae, Escherichia coli was the most isolated bacteria (68%). Fifty-eight Enterobacteriaceae were resistant to carbapenem (4.7%). Klebsiella pneumoniae, Escherichia coli, and Enterobacter cloacae were the most common carbapenemase-producing isolates (43.1%, 27.5%, and 20.7%, respectively). All isolates were resistant to ertapenem, 62% to imipenem, whereas the lowest rate of resistance to carbapenems was against meropenem (51%). Among carbapenemase-producing isolates, 13.8% also produced extended-spectrum beta-lactamase. Most carbapenemase-producing Enterobacteriaceae isolates harbored the gene blaOXA-48 (84.5%).
Conclusions: Our findings highlight the alarming situation of the probable misuse of antibiotics. Awareness-raising sessions about the appropriate use of antibiotics and improving hospital hygiene are highly needed.
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| ISSN: | 1972-2680 |