Geographical Patterns and Determinants of Selenium Deficiency in Tibet: A Cross‐Sectional Study Based on Urinary Selenium Analysis
Abstract Selenium is an essential micronutrient, yet its deficiency poses severe health risks, including Kashin‐Beck disease, a debilitating disorder endemic to selenium‐deficient regions like Tibet. Despite the known risks, the extent and drivers of selenium deficiency in Tibetan populations remain...
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| Format: | Article |
| Language: | English |
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Wiley
2025-02-01
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| Series: | Earth's Future |
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| Online Access: | https://doi.org/10.1029/2024EF005748 |
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| author | Yi Yang Ru Zhang Yangzong Deji You Li Yonghua Li |
| author_facet | Yi Yang Ru Zhang Yangzong Deji You Li Yonghua Li |
| author_sort | Yi Yang |
| collection | DOAJ |
| description | Abstract Selenium is an essential micronutrient, yet its deficiency poses severe health risks, including Kashin‐Beck disease, a debilitating disorder endemic to selenium‐deficient regions like Tibet. Despite the known risks, the extent and drivers of selenium deficiency in Tibetan populations remain poorly characterized. Here, we present the first large‐scale assessment of urinary selenium levels across Tibet, based on 637 systematically collected samples, revealing an average concentration of 7.71 μg/L, far below adequate thresholds. Dietary patterns, particularly reliance on the red meat and vegetable diet, emerged as the dominant factor influencing selenium levels, while aging was associated with a marked decline in selenium status. Geographical factors were found to exert indirect but significant effects. These findings highlight critical selenium deficiencies among Tibetan residents and emphasize the urgent need for targeted interventions, including the introduction of selenium‐enriched foods, to mitigate health risks—especially for older populations most at risk. |
| format | Article |
| id | doaj-art-de61d1adca9448ca9e513ef2216cbf35 |
| institution | DOAJ |
| issn | 2328-4277 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Earth's Future |
| spelling | doaj-art-de61d1adca9448ca9e513ef2216cbf352025-08-20T02:46:00ZengWileyEarth's Future2328-42772025-02-01132n/an/a10.1029/2024EF005748Geographical Patterns and Determinants of Selenium Deficiency in Tibet: A Cross‐Sectional Study Based on Urinary Selenium AnalysisYi Yang0Ru Zhang1Yangzong Deji2You Li3Yonghua Li4Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences Beijing ChinaSouth China Sea Marine Survey Center Ministry of Natural Resources Guangzhou ChinaTibet Autonomous Region Center for Disease Control and Prevention Lhasa ChinaInstitute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences Beijing ChinaInstitute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences Beijing ChinaAbstract Selenium is an essential micronutrient, yet its deficiency poses severe health risks, including Kashin‐Beck disease, a debilitating disorder endemic to selenium‐deficient regions like Tibet. Despite the known risks, the extent and drivers of selenium deficiency in Tibetan populations remain poorly characterized. Here, we present the first large‐scale assessment of urinary selenium levels across Tibet, based on 637 systematically collected samples, revealing an average concentration of 7.71 μg/L, far below adequate thresholds. Dietary patterns, particularly reliance on the red meat and vegetable diet, emerged as the dominant factor influencing selenium levels, while aging was associated with a marked decline in selenium status. Geographical factors were found to exert indirect but significant effects. These findings highlight critical selenium deficiencies among Tibetan residents and emphasize the urgent need for targeted interventions, including the introduction of selenium‐enriched foods, to mitigate health risks—especially for older populations most at risk.https://doi.org/10.1029/2024EF005748bio‐monitoringurinary seleniumdistribution patterninfluencing factorTibet |
| spellingShingle | Yi Yang Ru Zhang Yangzong Deji You Li Yonghua Li Geographical Patterns and Determinants of Selenium Deficiency in Tibet: A Cross‐Sectional Study Based on Urinary Selenium Analysis Earth's Future bio‐monitoring urinary selenium distribution pattern influencing factor Tibet |
| title | Geographical Patterns and Determinants of Selenium Deficiency in Tibet: A Cross‐Sectional Study Based on Urinary Selenium Analysis |
| title_full | Geographical Patterns and Determinants of Selenium Deficiency in Tibet: A Cross‐Sectional Study Based on Urinary Selenium Analysis |
| title_fullStr | Geographical Patterns and Determinants of Selenium Deficiency in Tibet: A Cross‐Sectional Study Based on Urinary Selenium Analysis |
| title_full_unstemmed | Geographical Patterns and Determinants of Selenium Deficiency in Tibet: A Cross‐Sectional Study Based on Urinary Selenium Analysis |
| title_short | Geographical Patterns and Determinants of Selenium Deficiency in Tibet: A Cross‐Sectional Study Based on Urinary Selenium Analysis |
| title_sort | geographical patterns and determinants of selenium deficiency in tibet a cross sectional study based on urinary selenium analysis |
| topic | bio‐monitoring urinary selenium distribution pattern influencing factor Tibet |
| url | https://doi.org/10.1029/2024EF005748 |
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