Electrospun Fibers of Enteric Polymer for Controlled Drug Delivery
The production of electrospun fibers of enteric polymer for controlled delivery of drugs represents a simple and low cost procedure with promising advantages relative to the longer therapeutic window provided by cylindrical geometry in association with intrinsic properties of pH-dependent drug carri...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | International Journal of Polymer Science |
| Online Access: | http://dx.doi.org/10.1155/2015/902365 |
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| _version_ | 1832554394468483072 |
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| author | Fábia F. P. da Costa Evando S. Araújo Marcio L. F. Nascimento Helinando P. de Oliveira |
| author_facet | Fábia F. P. da Costa Evando S. Araújo Marcio L. F. Nascimento Helinando P. de Oliveira |
| author_sort | Fábia F. P. da Costa |
| collection | DOAJ |
| description | The production of electrospun fibers of enteric polymer for controlled delivery of drugs represents a simple and low cost procedure with promising advantages relative to the longer therapeutic window provided by cylindrical geometry in association with intrinsic properties of pH-dependent drug carriers. In this work, we have explored the incorporation of additives (block copolymers of poly(ethylene)-b-poly(ethylene oxide)) into matrix of Eudragit L-100 and the effective action of hybrid composites on delivery of nifedipine, providing improvement in the overall process of controlled release of loaded drug. |
| format | Article |
| id | doaj-art-de550451a7314656b9cedbd077692971 |
| institution | Kabale University |
| issn | 1687-9422 1687-9430 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Polymer Science |
| spelling | doaj-art-de550451a7314656b9cedbd0776929712025-02-03T05:51:43ZengWileyInternational Journal of Polymer Science1687-94221687-94302015-01-01201510.1155/2015/902365902365Electrospun Fibers of Enteric Polymer for Controlled Drug DeliveryFábia F. P. da Costa0Evando S. Araújo1Marcio L. F. Nascimento2Helinando P. de Oliveira3Instituto de Pesquisa em Ciência dos Materiais, Universidade Federal do Vale do São Francisco, 48920-310 Juazeiro, BA, BrazilInstituto de Pesquisa em Ciência dos Materiais, Universidade Federal do Vale do São Francisco, 48920-310 Juazeiro, BA, BrazilPrograma de Pós-Graduação em Engenharia Industrial, Escola Politécnica, Universidade Federal da Bahia, 40210-630 Salvador, BA, BrazilInstituto de Pesquisa em Ciência dos Materiais, Universidade Federal do Vale do São Francisco, 48920-310 Juazeiro, BA, BrazilThe production of electrospun fibers of enteric polymer for controlled delivery of drugs represents a simple and low cost procedure with promising advantages relative to the longer therapeutic window provided by cylindrical geometry in association with intrinsic properties of pH-dependent drug carriers. In this work, we have explored the incorporation of additives (block copolymers of poly(ethylene)-b-poly(ethylene oxide)) into matrix of Eudragit L-100 and the effective action of hybrid composites on delivery of nifedipine, providing improvement in the overall process of controlled release of loaded drug.http://dx.doi.org/10.1155/2015/902365 |
| spellingShingle | Fábia F. P. da Costa Evando S. Araújo Marcio L. F. Nascimento Helinando P. de Oliveira Electrospun Fibers of Enteric Polymer for Controlled Drug Delivery International Journal of Polymer Science |
| title | Electrospun Fibers of Enteric Polymer for Controlled Drug Delivery |
| title_full | Electrospun Fibers of Enteric Polymer for Controlled Drug Delivery |
| title_fullStr | Electrospun Fibers of Enteric Polymer for Controlled Drug Delivery |
| title_full_unstemmed | Electrospun Fibers of Enteric Polymer for Controlled Drug Delivery |
| title_short | Electrospun Fibers of Enteric Polymer for Controlled Drug Delivery |
| title_sort | electrospun fibers of enteric polymer for controlled drug delivery |
| url | http://dx.doi.org/10.1155/2015/902365 |
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