Short review of the biomedical properties and application of magnesium alloys for bone tissue bioengineering
Aim: to review current scientific literature concerning the main advances and problems of magnesium (Mg) alloys for traumatology and orthopedics. Methodology of the study. Analytical review based the comprehensive investigation of public scientific and technological sources. Results of the study. Mo...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2019-08-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/2325 |
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| author | I. A. Khlusov D. V. Mitrichenko A. B. Prosolov O. O. Nikolaeva G. B. Slepchenko Yu. P. Sharkeev |
| author_facet | I. A. Khlusov D. V. Mitrichenko A. B. Prosolov O. O. Nikolaeva G. B. Slepchenko Yu. P. Sharkeev |
| author_sort | I. A. Khlusov |
| collection | DOAJ |
| description | Aim: to review current scientific literature concerning the main advances and problems of magnesium (Mg) alloys for traumatology and orthopedics. Methodology of the study. Analytical review based the comprehensive investigation of public scientific and technological sources. Results of the study. Modern knowledge about classification, in vitro and in vivo biodegradation, biomechanics, local and general biocompatibilities, clinical efficacy, and hazards of infectious complications in conditions of osteosynthesis with implants made of Mg alloys with or without protective (anticorrosion and antimicrobial) coatings is presented. Conclusion. Fast degradation and a risk of periprosthetic infection strongly limit clinical application of implants made of Mg and its alloys. Development of novel Mg alloys and their modification by incorporating antimicrobial elements into their body or protective coating is a promising direction to control biomedical characteristics of Mg alloys. |
| format | Article |
| id | doaj-art-de526e6199384365a1eb0ae7ddd64996 |
| institution | Kabale University |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2019-08-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-de526e6199384365a1eb0ae7ddd649962025-08-20T03:37:41ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842019-08-0118227428610.20538/1682-0363-2019-2-274-2861528Short review of the biomedical properties and application of magnesium alloys for bone tissue bioengineeringI. A. Khlusov0D. V. Mitrichenko1A. B. Prosolov2O. O. Nikolaeva3G. B. Slepchenko4Yu. P. Sharkeev5Siberian State Medical University; Research and Production Company SINTEL LLC; National Research Tomsk Polytechnic UniversityResearch and Production Company SINTEL LLCResearch and Production Company SINTEL LLCResearch and Production Company SINTEL LLCNational Research Tomsk Polytechnic UniversityNational Research Tomsk Polytechnic University; Institute of Strength Physics and Materials Science of SB RASAim: to review current scientific literature concerning the main advances and problems of magnesium (Mg) alloys for traumatology and orthopedics. Methodology of the study. Analytical review based the comprehensive investigation of public scientific and technological sources. Results of the study. Modern knowledge about classification, in vitro and in vivo biodegradation, biomechanics, local and general biocompatibilities, clinical efficacy, and hazards of infectious complications in conditions of osteosynthesis with implants made of Mg alloys with or without protective (anticorrosion and antimicrobial) coatings is presented. Conclusion. Fast degradation and a risk of periprosthetic infection strongly limit clinical application of implants made of Mg and its alloys. Development of novel Mg alloys and their modification by incorporating antimicrobial elements into their body or protective coating is a promising direction to control biomedical characteristics of Mg alloys.https://bulletin.ssmu.ru/jour/article/view/2325biodegradationin vitroin vivobiomechanicsbiocompatibilityosteosynthesis |
| spellingShingle | I. A. Khlusov D. V. Mitrichenko A. B. Prosolov O. O. Nikolaeva G. B. Slepchenko Yu. P. Sharkeev Short review of the biomedical properties and application of magnesium alloys for bone tissue bioengineering Бюллетень сибирской медицины biodegradation in vitro in vivo biomechanics biocompatibility osteosynthesis |
| title | Short review of the biomedical properties and application of magnesium alloys for bone tissue bioengineering |
| title_full | Short review of the biomedical properties and application of magnesium alloys for bone tissue bioengineering |
| title_fullStr | Short review of the biomedical properties and application of magnesium alloys for bone tissue bioengineering |
| title_full_unstemmed | Short review of the biomedical properties and application of magnesium alloys for bone tissue bioengineering |
| title_short | Short review of the biomedical properties and application of magnesium alloys for bone tissue bioengineering |
| title_sort | short review of the biomedical properties and application of magnesium alloys for bone tissue bioengineering |
| topic | biodegradation in vitro in vivo biomechanics biocompatibility osteosynthesis |
| url | https://bulletin.ssmu.ru/jour/article/view/2325 |
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