ROLE OF VITAMIN D IN THE EFFICIENCY OF ANTIRESORPTIVE THERAPY

Vitamin D deficiency is one of the substantiated risk factors of osteoporosis. This vitamin is required to provide intestinal calcium absorption, bone metabolism regulation, and neuromuscular functions in the body. Vitamin D deficiency results in increased bone metabolism, causing bone loss progress...

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Main Author: N V Toroptsova
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2009-06-01
Series:Современная ревматология
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Online Access:https://mrj.ima-press.net/mrj/article/view/231
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author N V Toroptsova
author_facet N V Toroptsova
author_sort N V Toroptsova
collection DOAJ
description Vitamin D deficiency is one of the substantiated risk factors of osteoporosis. This vitamin is required to provide intestinal calcium absorption, bone metabolism regulation, and neuromuscular functions in the body. Vitamin D deficiency results in increased bone metabolism, causing bone loss progression and increasing the risk of fractures. Moreover, patients with vitamin D deficiency have a higher probability of fallings and loss of muscle mass, increasing in turn the risk of fractures. The combined formulation of alendronate and vitamin D as tablets is as effective as the mono-formulation of alendronate, but, furthermore, it has an additional advantage associated with the guaranteed vitamin D intake. At the same time the bioavailability of each component does not differ from the similar index when these agents are used alone.
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series Современная ревматология
spelling doaj-art-de4f1b5fc76049ec9a1b0d3ccac7129b2025-08-20T03:21:18ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2009-06-0132788110.14412/1996-7012-2009-5461536ROLE OF VITAMIN D IN THE EFFICIENCY OF ANTIRESORPTIVE THERAPYN V ToroptsovaVitamin D deficiency is one of the substantiated risk factors of osteoporosis. This vitamin is required to provide intestinal calcium absorption, bone metabolism regulation, and neuromuscular functions in the body. Vitamin D deficiency results in increased bone metabolism, causing bone loss progression and increasing the risk of fractures. Moreover, patients with vitamin D deficiency have a higher probability of fallings and loss of muscle mass, increasing in turn the risk of fractures. The combined formulation of alendronate and vitamin D as tablets is as effective as the mono-formulation of alendronate, but, furthermore, it has an additional advantage associated with the guaranteed vitamin D intake. At the same time the bioavailability of each component does not differ from the similar index when these agents are used alone.https://mrj.ima-press.net/mrj/article/view/231osteoporosischolecalciferolalendronate
spellingShingle N V Toroptsova
ROLE OF VITAMIN D IN THE EFFICIENCY OF ANTIRESORPTIVE THERAPY
Современная ревматология
osteoporosis
cholecalciferol
alendronate
title ROLE OF VITAMIN D IN THE EFFICIENCY OF ANTIRESORPTIVE THERAPY
title_full ROLE OF VITAMIN D IN THE EFFICIENCY OF ANTIRESORPTIVE THERAPY
title_fullStr ROLE OF VITAMIN D IN THE EFFICIENCY OF ANTIRESORPTIVE THERAPY
title_full_unstemmed ROLE OF VITAMIN D IN THE EFFICIENCY OF ANTIRESORPTIVE THERAPY
title_short ROLE OF VITAMIN D IN THE EFFICIENCY OF ANTIRESORPTIVE THERAPY
title_sort role of vitamin d in the efficiency of antiresorptive therapy
topic osteoporosis
cholecalciferol
alendronate
url https://mrj.ima-press.net/mrj/article/view/231
work_keys_str_mv AT nvtoroptsova roleofvitamindintheefficiencyofantiresorptivetherapy