Clinical, cytogenetic and molecular genetic characterization of a tandem fusion translocation in a male Holstein cattle with congenital hypospadias and a ventricular septal defect.

Clinical, cytogenetic and molecular genetic characterization of a tandem fusion translocation in a male Holstein cattle with congenital hypospadias and a ventricular septal defect.

Hypospadias, disorder of sex development (DSD), is a sporadic congenital abnormality of the genital region in male ruminants, which is characterized by a non-fused urethra during fetal development. Detailed clinical examination classified the hypospadias phenotype of a male Holstein calf studied her...

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Main Authors: Alessandra Iannuzzi, Marina Braun, Viviana Genualdo, Angela Perucatti, Sina Reinartz, Ioannis Proios, Maike Heppelmann, Jürgen Rehage, Kirsten Hülskötter, Andreas Beineke, Julia Metzger, Ottmar Distl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0227117&type=printable
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