False-Positive and False-Negative MRD Results in Children with Acute Lymphoblastic Leukemia: Navigating Between Scylla and Charybdis (Brief Review and Clinical Experience)

False-Positive and False-Negative MRD Results in Children with Acute Lymphoblastic Leukemia: Navigating Between Scylla and Charybdis (Brief Review and Clinical Experience)

Background/Objectives: Acute lymphoblastic leukemia (ALL) is the most common malignant disease in children. Contemporary antitumor treatment protocols provide long-term survival rates in over 90% of patients with ALL. High effectiveness of the treatment has been achieved as a result of chemotherapy...

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Main Authors: Yulia S. Korkina, Timur T. Valiev, Natalia A. Batmanova, Mikhail V. Kiselevskiy, Irina Z. Shubina, Kirill I. Kirgizov, Svetlana R. Varfolomeeva
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Children
Subjects:
minimal residual disease
false-positive MRD
false-negative MRD
flow cytometry
acute lymphoblastic leukemia
children
Online Access:https://www.mdpi.com/2227-9067/12/7/860
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