Nanotechnology-based herbal medicine: Preparation, synthesis, and applications in food and medicine
Nanotechnology has instigated profound developments among herbal medicineregarding bioavailability, stability, and therapeutic efficacy. This review deals with nano-herbal formulations' preparation, applications, and therapeutic capabilities for medical problems and foods like food packaging an...
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Elsevier
2025-03-01
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| Series: | Journal of Agriculture and Food Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666154325000328 |
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| author | Farhang H. Awlqadr Kithar Rasheed Majeed Ammar B. Altemimi Arkan Mohammed Hassan Syamand Ahmed Qadir Mohammed N. Saeed Aryan Mahmood Faraj Tablo H. Salih Alaa Jabbar Abd Al‐Manhel Mazin A.A. Najm Efstathia Tsakali Jan F.M. Van Impe Ahmed A. Abd El-Maksoud Tarek Gamal Abedelmaksoud |
| author_facet | Farhang H. Awlqadr Kithar Rasheed Majeed Ammar B. Altemimi Arkan Mohammed Hassan Syamand Ahmed Qadir Mohammed N. Saeed Aryan Mahmood Faraj Tablo H. Salih Alaa Jabbar Abd Al‐Manhel Mazin A.A. Najm Efstathia Tsakali Jan F.M. Van Impe Ahmed A. Abd El-Maksoud Tarek Gamal Abedelmaksoud |
| author_sort | Farhang H. Awlqadr |
| collection | DOAJ |
| description | Nanotechnology has instigated profound developments among herbal medicineregarding bioavailability, stability, and therapeutic efficacy. This review deals with nano-herbal formulations' preparation, applications, and therapeutic capabilities for medical problems and foods like food packaging and preservation. The formulations are developed using advanced nanotechnology techniques, such as solvent evaporation, nanoemulsion formation, and encapsulation. Phytosomes, liposomes, nanocapsules, and nanoemulsions have ensured that bioactive ingredients' stability has been secured, bioavailability and targeted administration have been improved, and negative side effects have been cut considerably. The ability of nanoherbal formulations to deliver drugs to tumor cells in an improved permeability and retention manner, such as, cancer therapy while minimizing tissue damage, has been largely practiced in many laboratories. Enhanced drug solubility, distribution to the site of interest, and successful therapeutic outcomes have had a major impact on inflammatory disorders, cardiovascular diseases, diabetes, skin problems, and neurodegenerative diseases. Dendrimers and solid lipid nanoparticles transport anti-inflammatory and antioxidant substances, whereas polymeric nanoparticles protect against Alzheimer's and Parkinson's diseases. Nanocarriers increase the absorption of curcumin and resveratrol, decreasing oxidative stress and improving cardiac function. Nanotechnology has used such reinforcing materials to improve the performance of protective food packages and, consequently, ensure their longer service time. On the one hand, antimicrobial and antioxidant herbal nanoparticles will prevent spoilage and degradation during storage.On the other hand, nanoemulsions form a medium for vitamins, minerals, and antioxidants to be bioavailable in fortified meals. The following practices have contributed to preserving food products' nutritional and functional attributes. Nonetheless, nanotechnology has found its way into these chemical compositions, bringing about the issues of scaling up, cost-efficiency, regulatory compliance, and safety concerns. Biodistribution, metabolism and the coccion of long-term effects studies must confirm safe and sustainable usage. To stimulate full utilization of nanotechnology in medicine and food science, further study must be undertaken to clear the existing drawbacks and discover other fields of the most appropriate applications of nanotechnology. Nanotechnology and herbal medicine join forces and form a potent medical and nutritional solution to various diseases, food production, and conservation. Such advancements would modify treatment and nutritional strategies, allowing a more secure, effective, and long life. |
| format | Article |
| id | doaj-art-de49b4d862aa46fa8e6f6e64def5b9fe |
| institution | Kabale University |
| issn | 2666-1543 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Agriculture and Food Research |
| spelling | doaj-art-de49b4d862aa46fa8e6f6e64def5b9fe2025-02-07T04:48:19ZengElsevierJournal of Agriculture and Food Research2666-15432025-03-0119101661Nanotechnology-based herbal medicine: Preparation, synthesis, and applications in food and medicineFarhang H. Awlqadr0Kithar Rasheed Majeed1Ammar B. Altemimi2Arkan Mohammed Hassan3Syamand Ahmed Qadir4Mohammed N. Saeed5Aryan Mahmood Faraj6Tablo H. Salih7Alaa Jabbar Abd Al‐Manhel8Mazin A.A. Najm9Efstathia Tsakali10Jan F.M. Van Impe11Ahmed A. Abd El-Maksoud12Tarek Gamal Abedelmaksoud13Food Science and Quality Control, Halabja Technical College, Sulaimani Polytechnic University, Sulaymaniyah, IraqDepartment of Food Science, College of Agriculture, University of Basrah, Basrah, 61004, IraqDepartment of Food Science, College of Agriculture, University of Basrah, Basrah, 61004, Iraq; Corresponding author.Department of Chemistry, College of Science, University of Garmian, Darbandikhan Road, Kurdistan of Iraq, 46021, Kalar City, Sulaimaniyah Province, IraqMedical Laboratory Techniques Department, Halabja Technical Institute, Research Center, Sulaimani Polytechnic University, Sulaymaniyah, IraqDepartment of Chemistry, College of Science, University of Garmian, Darbandikhan Road, Kurdistan of Iraq, 46021, Kalar City, Sulaimaniyah Province, IraqMedical Laboratory Science Department, Halabja Technical College of Applied Sciences, Sulaimani Polytechnic University Sulaymaniyah, IraqFood Science and Quality Control, Halabja Technical College, Sulaimani Polytechnic University, Sulaymaniyah, IraqDepartment of Food Science, College of Agriculture, University of Basrah, Basrah, 61004, IraqDepartment of Pharmacy, Mazaya University College, IraqDepartment of Food Science and Technology, University of West Attica, Egaleo, 122 43, Greece; Department of Chemical Engineering, BioTeC+ Chemical & Biochemical Process, KU Leuven, 9000, Gent, BelgiumDepartment of Chemical Engineering, BioTeC+ Chemical & Biochemical Process, KU Leuven, 9000, Gent, Belgium; Corresponding author.Dairy Science Department, Faculty of Agriculture, Cairo University, Giza, 12613, EgyptFood Science Department, Faculty of Agriculture, Cairo University, Giza, 12613, EgyptNanotechnology has instigated profound developments among herbal medicineregarding bioavailability, stability, and therapeutic efficacy. This review deals with nano-herbal formulations' preparation, applications, and therapeutic capabilities for medical problems and foods like food packaging and preservation. The formulations are developed using advanced nanotechnology techniques, such as solvent evaporation, nanoemulsion formation, and encapsulation. Phytosomes, liposomes, nanocapsules, and nanoemulsions have ensured that bioactive ingredients' stability has been secured, bioavailability and targeted administration have been improved, and negative side effects have been cut considerably. The ability of nanoherbal formulations to deliver drugs to tumor cells in an improved permeability and retention manner, such as, cancer therapy while minimizing tissue damage, has been largely practiced in many laboratories. Enhanced drug solubility, distribution to the site of interest, and successful therapeutic outcomes have had a major impact on inflammatory disorders, cardiovascular diseases, diabetes, skin problems, and neurodegenerative diseases. Dendrimers and solid lipid nanoparticles transport anti-inflammatory and antioxidant substances, whereas polymeric nanoparticles protect against Alzheimer's and Parkinson's diseases. Nanocarriers increase the absorption of curcumin and resveratrol, decreasing oxidative stress and improving cardiac function. Nanotechnology has used such reinforcing materials to improve the performance of protective food packages and, consequently, ensure their longer service time. On the one hand, antimicrobial and antioxidant herbal nanoparticles will prevent spoilage and degradation during storage.On the other hand, nanoemulsions form a medium for vitamins, minerals, and antioxidants to be bioavailable in fortified meals. The following practices have contributed to preserving food products' nutritional and functional attributes. Nonetheless, nanotechnology has found its way into these chemical compositions, bringing about the issues of scaling up, cost-efficiency, regulatory compliance, and safety concerns. Biodistribution, metabolism and the coccion of long-term effects studies must confirm safe and sustainable usage. To stimulate full utilization of nanotechnology in medicine and food science, further study must be undertaken to clear the existing drawbacks and discover other fields of the most appropriate applications of nanotechnology. Nanotechnology and herbal medicine join forces and form a potent medical and nutritional solution to various diseases, food production, and conservation. Such advancements would modify treatment and nutritional strategies, allowing a more secure, effective, and long life.http://www.sciencedirect.com/science/article/pii/S2666154325000328Nanoherbal formulationsHerbal medicineBioavailabilityTargeted delivery |
| spellingShingle | Farhang H. Awlqadr Kithar Rasheed Majeed Ammar B. Altemimi Arkan Mohammed Hassan Syamand Ahmed Qadir Mohammed N. Saeed Aryan Mahmood Faraj Tablo H. Salih Alaa Jabbar Abd Al‐Manhel Mazin A.A. Najm Efstathia Tsakali Jan F.M. Van Impe Ahmed A. Abd El-Maksoud Tarek Gamal Abedelmaksoud Nanotechnology-based herbal medicine: Preparation, synthesis, and applications in food and medicine Journal of Agriculture and Food Research Nanoherbal formulations Herbal medicine Bioavailability Targeted delivery |
| title | Nanotechnology-based herbal medicine: Preparation, synthesis, and applications in food and medicine |
| title_full | Nanotechnology-based herbal medicine: Preparation, synthesis, and applications in food and medicine |
| title_fullStr | Nanotechnology-based herbal medicine: Preparation, synthesis, and applications in food and medicine |
| title_full_unstemmed | Nanotechnology-based herbal medicine: Preparation, synthesis, and applications in food and medicine |
| title_short | Nanotechnology-based herbal medicine: Preparation, synthesis, and applications in food and medicine |
| title_sort | nanotechnology based herbal medicine preparation synthesis and applications in food and medicine |
| topic | Nanoherbal formulations Herbal medicine Bioavailability Targeted delivery |
| url | http://www.sciencedirect.com/science/article/pii/S2666154325000328 |
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