Evaluation of Hepatic Mitochondria and Hematological Parameters in Zidovudine-Treated B6C3F1 Mice

Evaluation of Hepatic Mitochondria and Hematological Parameters in Zidovudine-Treated B6C3F1 Mice

The effects of 12-week exposure to zidovudine (AZT) at 400, 500, and 600 mg/kg/d were examined on expression of 542 mitochondria-related genes and mitochondrial DNA (mtDNA) copy number in the liver of male and female B6C3F1 mice to understand mitochondrial role in sex-related differences in developm...

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Bibliographic Details
Main Authors:	Varsha G. Desai, Taewon Lee, Carrie L. Moland, William S. Branham, Roberta A. Mittelstaedt, Sherry M. Lewis, Julian E. A. Leakey, James C. Fuscoe
Format:	Article
Language:	English
Published:	Wiley 2012-01-01
Series:	AIDS Research and Treatment
Online Access:	http://dx.doi.org/10.1155/2012/317695
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