Maternofoetal Complications and Their Association with Proteinuria in a Tertiary Care Hospital of a Developing Country

Objective. To investigate association between maternofoetal complications and the amount of proteinuria measured by spot urine protein creatinine ratio in patients with preeclampsia. Methods. 200 consecutive patients with preeclampsia were recruited in the study. The complications like first episod...

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Main Authors: Archana Kumari, Avinash Chakrawarty, Abha Singh, Ritu Singh
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Pregnancy
Online Access:http://dx.doi.org/10.1155/2014/431837
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author Archana Kumari
Avinash Chakrawarty
Abha Singh
Ritu Singh
author_facet Archana Kumari
Avinash Chakrawarty
Abha Singh
Ritu Singh
author_sort Archana Kumari
collection DOAJ
description Objective. To investigate association between maternofoetal complications and the amount of proteinuria measured by spot urine protein creatinine ratio in patients with preeclampsia. Methods. 200 consecutive patients with preeclampsia were recruited in the study. The complications like first episode of severe hypertension, renal insufficiency, raised level of aspartate transaminase, signs of neurological involvement, thrombocytopenia, eclampsia, and need to shift in intensive care units were studied. The maternal outcome was studied in terms of type of labour, outcome of pregnancy, mode of delivery, indication of cesarean section, and maternal mortality. The foetal complications and outcome parameters were birth weight, Apgar score at the time of birth and at five minutes, need of high dependency unit care, and perinatal mortality. Result. The frequency of various maternal and foetal complications was between 14–53% and 22–92%, respectively. Maternal mortality was 3%, whereas perinatal mortality was 23%. Statistically significant association was found between the frequencies of various complications in mother and newborn and spot UPCR. Conclusion. The rate of various maternofoetal complications in preeclampsia is higher in developing countries than in developed world. Maternofoetal complications and outcome correlate with maternal spot UPCR.
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spelling doaj-art-de319ae76a5445e59518d038d4634a932025-08-20T02:21:21ZengWileyJournal of Pregnancy2090-27272090-27352014-01-01201410.1155/2014/431837431837Maternofoetal Complications and Their Association with Proteinuria in a Tertiary Care Hospital of a Developing CountryArchana Kumari0Avinash Chakrawarty1Abha Singh2Ritu Singh3Department of Obstetrics and Gynaecology, Lady Hardinge Medical College and Associated Hospitals, New Delhi 110001, IndiaDepartment of Medicine, All India Institute of Medical Sciences, New Delhi 110029, IndiaDepartment of Obstetrics and Gynaecology, Lady Hardinge Medical College and Associated Hospitals, New Delhi 110001, IndiaDepartment of Biochemistry, Lady Hardinge Medical college and Associated Hospitals, New Delhi 110001, IndiaObjective. To investigate association between maternofoetal complications and the amount of proteinuria measured by spot urine protein creatinine ratio in patients with preeclampsia. Methods. 200 consecutive patients with preeclampsia were recruited in the study. The complications like first episode of severe hypertension, renal insufficiency, raised level of aspartate transaminase, signs of neurological involvement, thrombocytopenia, eclampsia, and need to shift in intensive care units were studied. The maternal outcome was studied in terms of type of labour, outcome of pregnancy, mode of delivery, indication of cesarean section, and maternal mortality. The foetal complications and outcome parameters were birth weight, Apgar score at the time of birth and at five minutes, need of high dependency unit care, and perinatal mortality. Result. The frequency of various maternal and foetal complications was between 14–53% and 22–92%, respectively. Maternal mortality was 3%, whereas perinatal mortality was 23%. Statistically significant association was found between the frequencies of various complications in mother and newborn and spot UPCR. Conclusion. The rate of various maternofoetal complications in preeclampsia is higher in developing countries than in developed world. Maternofoetal complications and outcome correlate with maternal spot UPCR.http://dx.doi.org/10.1155/2014/431837
spellingShingle Archana Kumari
Avinash Chakrawarty
Abha Singh
Ritu Singh
Maternofoetal Complications and Their Association with Proteinuria in a Tertiary Care Hospital of a Developing Country
Journal of Pregnancy
title Maternofoetal Complications and Their Association with Proteinuria in a Tertiary Care Hospital of a Developing Country
title_full Maternofoetal Complications and Their Association with Proteinuria in a Tertiary Care Hospital of a Developing Country
title_fullStr Maternofoetal Complications and Their Association with Proteinuria in a Tertiary Care Hospital of a Developing Country
title_full_unstemmed Maternofoetal Complications and Their Association with Proteinuria in a Tertiary Care Hospital of a Developing Country
title_short Maternofoetal Complications and Their Association with Proteinuria in a Tertiary Care Hospital of a Developing Country
title_sort maternofoetal complications and their association with proteinuria in a tertiary care hospital of a developing country
url http://dx.doi.org/10.1155/2014/431837
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