The effect of exercise on depression and gut microbiota: Possible mechanisms
Exercise can effectively prevent and treat depression and anxiety, with gut microbiota playing a crucial role in this process. Studies have shown that exercise can influence the diversity and composition of gut microbiota, which in turn affects depression through immune, endocrine, and neural pathwa...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Brain Research Bulletin |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0361923024002648 |
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| author | Mingchen Yao Yaqi Qu Yalin Zheng Hao Guo |
| author_facet | Mingchen Yao Yaqi Qu Yalin Zheng Hao Guo |
| author_sort | Mingchen Yao |
| collection | DOAJ |
| description | Exercise can effectively prevent and treat depression and anxiety, with gut microbiota playing a crucial role in this process. Studies have shown that exercise can influence the diversity and composition of gut microbiota, which in turn affects depression through immune, endocrine, and neural pathways in the gut-brain axis. The effectiveness of exercise varies based on its type, intensity, and duration, largely due to the different changes in gut microbiota. This article summarizes the possible mechanisms by which exercise affects gut microbiota and how gut microbiota influences depression. Additionally, we reviewed literature on the effects of exercise on depression at different intensities, types, and durations to provide a reference for future exercise-based therapies for depression. |
| format | Article |
| id | doaj-art-de317aa72463458299ea85276a3c0308 |
| institution | Kabale University |
| issn | 1873-2747 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brain Research Bulletin |
| spelling | doaj-art-de317aa72463458299ea85276a3c03082025-01-10T04:36:53ZengElsevierBrain Research Bulletin1873-27472025-01-01220111130The effect of exercise on depression and gut microbiota: Possible mechanismsMingchen Yao0Yaqi Qu1Yalin Zheng2Hao Guo3School of Sports Medicine and Rehabilitation, Beijing Sport University, Beijing, ChinaSchool of Sports Medicine and Rehabilitation, Beijing Sport University, Beijing, ChinaSchool of Sports Medicine and Rehabilitation, Beijing Sport University, Beijing, ChinaCorresponding author.; School of Sports Medicine and Rehabilitation, Beijing Sport University, Beijing, ChinaExercise can effectively prevent and treat depression and anxiety, with gut microbiota playing a crucial role in this process. Studies have shown that exercise can influence the diversity and composition of gut microbiota, which in turn affects depression through immune, endocrine, and neural pathways in the gut-brain axis. The effectiveness of exercise varies based on its type, intensity, and duration, largely due to the different changes in gut microbiota. This article summarizes the possible mechanisms by which exercise affects gut microbiota and how gut microbiota influences depression. Additionally, we reviewed literature on the effects of exercise on depression at different intensities, types, and durations to provide a reference for future exercise-based therapies for depression.http://www.sciencedirect.com/science/article/pii/S0361923024002648ExerciseDepressionGut microbiotaGut-brain axis |
| spellingShingle | Mingchen Yao Yaqi Qu Yalin Zheng Hao Guo The effect of exercise on depression and gut microbiota: Possible mechanisms Brain Research Bulletin Exercise Depression Gut microbiota Gut-brain axis |
| title | The effect of exercise on depression and gut microbiota: Possible mechanisms |
| title_full | The effect of exercise on depression and gut microbiota: Possible mechanisms |
| title_fullStr | The effect of exercise on depression and gut microbiota: Possible mechanisms |
| title_full_unstemmed | The effect of exercise on depression and gut microbiota: Possible mechanisms |
| title_short | The effect of exercise on depression and gut microbiota: Possible mechanisms |
| title_sort | effect of exercise on depression and gut microbiota possible mechanisms |
| topic | Exercise Depression Gut microbiota Gut-brain axis |
| url | http://www.sciencedirect.com/science/article/pii/S0361923024002648 |
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