FOXA2 promotes metastatic competence in small cell lung cancer

FOXA2 promotes metastatic competence in small cell lung cancer

Abstract Small cell lung cancer (SCLC) is known for its high metastatic potential, with most patients demonstrating clinically evident metastases in multiple organs at diagnosis. The factors contributing to this exceptional metastatic capacity have not been defined. To bridge this gap, we compare ge...

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Bibliographic Details
Main Authors: Kenta Kawasaki, Sohrab Salehi, Yingqian A. Zhan, Kevin Chen, Jun Ho Lee, Eralda Salataj, Hong Zhong, Parvathy Manoj, Dennis Kinyua, Barbara P. Mello, Harsha Sridhar, Sam E. Tischfield, Irina Linkov, Nicholas Ceglia, Matthew Zatzman, Eliyahu Havasov, Neil J. Shah, Fanli Meng, Brian Loomis, Umesh K. Bhanot, Esther Redin, Elisa de Stanchina, Pierre-Jacques Hamard, Richard P. Koche, Andrew McPherson, Álvaro Quintanal-Villalonga, Sohrab P. Shah, Joan Massagué, Charles M. Rudin
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60141-5
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