An anterior mediastinal cystic lesion pathologically confirmed as a mediastinal pancreatic pseudocyst after thoracoscopic resection: a rare case report and literature review
BackgroundMediastinal lesions have diverse etiologies, with thymoma, cystic teratoma, and lymphoma being relatively prevalent. In contrast, a pancreatic pseudocyst within the mediastinum is exceedingly rare and can often be mistaken for a thymic cyst or teratoma.Case presentationA 17-year-old female...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2025.1613764/full |
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| author | Kui Zhai Xingpeng Miao Guiling Xue Zhanyu Yuan Mao Jia Mingyan Chen Renzhong Zha |
| author_facet | Kui Zhai Xingpeng Miao Guiling Xue Zhanyu Yuan Mao Jia Mingyan Chen Renzhong Zha |
| author_sort | Kui Zhai |
| collection | DOAJ |
| description | BackgroundMediastinal lesions have diverse etiologies, with thymoma, cystic teratoma, and lymphoma being relatively prevalent. In contrast, a pancreatic pseudocyst within the mediastinum is exceedingly rare and can often be mistaken for a thymic cyst or teratoma.Case presentationA 17-year-old female presented with a cough and sputum production. Chest CT revealed an anterior mediastinal mass, initially raising the suspicion of a thymic cyst. Thoracoscopic exploration and resection revealed a cystic lesion with a thick wall and brownish fluid. Both frozen section and final histopathological analysis confirmed a mediastinal cyst. Immunohistochemical markers (SYN positive, CK7 positive) led to a diagnosis of mediastinal pancreatic pseudocyst. The patient experienced significant recovery post-surgery, with a marked improvement in symptoms.ConclusionThis case highlights the importance of including mediastinal pancreatic pseudocyst in the differential diagnosis of anterior mediastinal cystic lesions. A thorough clinical and radiological assessment, along with surgical pathology and immunohistochemical profiling, is essential for accurate diagnosis and appropriate management. |
| format | Article |
| id | doaj-art-de1b8bb8916547ccbe644d5d3248d912 |
| institution | Kabale University |
| issn | 2296-2360 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj-art-de1b8bb8916547ccbe644d5d3248d9122025-08-20T03:29:07ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602025-07-011310.3389/fped.2025.16137641613764An anterior mediastinal cystic lesion pathologically confirmed as a mediastinal pancreatic pseudocyst after thoracoscopic resection: a rare case report and literature reviewKui Zhai0Xingpeng Miao1Guiling Xue2Zhanyu Yuan3Mao Jia4Mingyan Chen5Renzhong Zha6Department of Thoracic Surgery, People’s Hospital of Xingyi City, Xingyi, Guizhou, ChinaDepartment of Thoracic Surgery, People’s Hospital of Xingyi City, Xingyi, Guizhou, ChinaDepartment of Thoracic Surgery, People’s Hospital of Xingyi City, Xingyi, Guizhou, ChinaDepartment of Pathology, People’s Hospital of Xingyi City, Xingyi, Guizhou, ChinaDepartment of Pathology, People’s Hospital of Xingyi City, Xingyi, Guizhou, ChinaDepartment of Price Management, People’s Hospital of Xingyi City, Xingyi, Guizhou, ChinaDepartment of Thoracic Surgery, People’s Hospital of Xingyi City, Xingyi, Guizhou, ChinaBackgroundMediastinal lesions have diverse etiologies, with thymoma, cystic teratoma, and lymphoma being relatively prevalent. In contrast, a pancreatic pseudocyst within the mediastinum is exceedingly rare and can often be mistaken for a thymic cyst or teratoma.Case presentationA 17-year-old female presented with a cough and sputum production. Chest CT revealed an anterior mediastinal mass, initially raising the suspicion of a thymic cyst. Thoracoscopic exploration and resection revealed a cystic lesion with a thick wall and brownish fluid. Both frozen section and final histopathological analysis confirmed a mediastinal cyst. Immunohistochemical markers (SYN positive, CK7 positive) led to a diagnosis of mediastinal pancreatic pseudocyst. The patient experienced significant recovery post-surgery, with a marked improvement in symptoms.ConclusionThis case highlights the importance of including mediastinal pancreatic pseudocyst in the differential diagnosis of anterior mediastinal cystic lesions. A thorough clinical and radiological assessment, along with surgical pathology and immunohistochemical profiling, is essential for accurate diagnosis and appropriate management.https://www.frontiersin.org/articles/10.3389/fped.2025.1613764/fullanterior mediastinal cystic masspancreatic pseudocystmediastinal pancreatic lesionCTx-ray |
| spellingShingle | Kui Zhai Xingpeng Miao Guiling Xue Zhanyu Yuan Mao Jia Mingyan Chen Renzhong Zha An anterior mediastinal cystic lesion pathologically confirmed as a mediastinal pancreatic pseudocyst after thoracoscopic resection: a rare case report and literature review Frontiers in Pediatrics anterior mediastinal cystic mass pancreatic pseudocyst mediastinal pancreatic lesion CT x-ray |
| title | An anterior mediastinal cystic lesion pathologically confirmed as a mediastinal pancreatic pseudocyst after thoracoscopic resection: a rare case report and literature review |
| title_full | An anterior mediastinal cystic lesion pathologically confirmed as a mediastinal pancreatic pseudocyst after thoracoscopic resection: a rare case report and literature review |
| title_fullStr | An anterior mediastinal cystic lesion pathologically confirmed as a mediastinal pancreatic pseudocyst after thoracoscopic resection: a rare case report and literature review |
| title_full_unstemmed | An anterior mediastinal cystic lesion pathologically confirmed as a mediastinal pancreatic pseudocyst after thoracoscopic resection: a rare case report and literature review |
| title_short | An anterior mediastinal cystic lesion pathologically confirmed as a mediastinal pancreatic pseudocyst after thoracoscopic resection: a rare case report and literature review |
| title_sort | anterior mediastinal cystic lesion pathologically confirmed as a mediastinal pancreatic pseudocyst after thoracoscopic resection a rare case report and literature review |
| topic | anterior mediastinal cystic mass pancreatic pseudocyst mediastinal pancreatic lesion CT x-ray |
| url | https://www.frontiersin.org/articles/10.3389/fped.2025.1613764/full |
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