The Mechanism of Calcium Handling Proteins and NF-κB in Calcium Dyshomeostasis of Cardiomyocytes Caused by Acute MDMA Exposure

The Mechanism of Calcium Handling Proteins and NF-κB in Calcium Dyshomeostasis of Cardiomyocytes Caused by Acute MDMA Exposure

ObjectiveTo explore the mechanism of myocardial toxicity caused by N-methyl-3,4-methyle-nedioxyamphetamine （MDMA）, the changes of intracellular calcium oscillation mode and calcium handling proteins during acute exposure to different concentrations of MDMA were detected, and the involvement of nucle...

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Bibliographic Details
Main Authors: WANG Rong-shuai, HUANG Si-zhe, WANG Yun-yun, DENG Yan-fei, DING Zi-jiao, ZHANG Jie, LIU Yong, REN Liang, LIU Liang
Format: Article
Language:zho
Published: Editorial Office of Journal of Forensic Medicine 2025-04-01
Series:Fayixue Zazhi
Subjects:
forensic pathology
forensic toxicology
n-methyl-3,4-methylenedioxyamphetamine （mdma）
cytotoxicity
calcium homeostasis
calcium handling protein
nuclear factor κb （nf-κb）
protein kinase c （pkc）
Online Access:http://www.fyxzz.cn/CN/10.12116/j.issn.1004-5619.2024.440503
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