The TgsGP gene is essential for resistance to human serum in Trypanosoma brucei gambiense.

The TgsGP gene is essential for resistance to human serum in Trypanosoma brucei gambiense.

Trypanosoma brucei gambiense causes 97% of all cases of African sleeping sickness, a fatal disease of sub-Saharan Africa. Most species of trypanosome, such as T. b. brucei, are unable to infect humans due to the trypanolytic serum protein apolipoprotein-L1 (APOL1) delivered via two trypanosome lytic...

Full description

Saved in:
Bibliographic Details
Main Authors: Paul Capewell, Caroline Clucas, Eric DeJesus, Rudo Kieft, Stephen Hajduk, Nicola Veitch, Pieter C Steketee, Anneli Cooper, William Weir, Annette MacLeod
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1003686
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items