Comparison of QIAstat-Dx and BioFire FilmArray Gastrointestinal Panels in a Pediatric Population
Accurate laboratory diagnosis of gastroenteritis is important to ensure that patients receive appropriate treatment and proper isolation precautions. This study evaluated the performance of the QIAGEN QIAstat-Dx gastrointestinal panel (QGP) in comparison to the bioMerieux BioFire FilmArray gastroint...
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| Language: | English |
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MDPI AG
2024-11-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/12/11/2282 |
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| author | Mohammed Suleiman Muhammad Iqbal Patrick Tang Andrés Pérez-López |
| author_facet | Mohammed Suleiman Muhammad Iqbal Patrick Tang Andrés Pérez-López |
| author_sort | Mohammed Suleiman |
| collection | DOAJ |
| description | Accurate laboratory diagnosis of gastroenteritis is important to ensure that patients receive appropriate treatment and proper isolation precautions. This study evaluated the performance of the QIAGEN QIAstat-Dx gastrointestinal panel (QGP) in comparison to the bioMerieux BioFire FilmArray gastrointestinal panel (BGP) for the detection of gastrointestinal pathogens in 110 pediatric patients being evaluated for gastroenteritis at our hospital. We compared 23 different bacterial, viral, and parasite enteropathogens detected by the QGP against the BGP. The overall positive percent agreement (PPA) for all compared targets was 96.2% and the overall negative percent agreement (NPA) for all compared targets was 99.7%. Our study shows that QIAstat-Dx QGP provides comparable results to the BioFire BGP in our pediatric population. Additionally, the PCR cycle threshold (Ct) value reported by the QGP is potentially a helpful tool in estimating the load of the detected pathogen in stool samples. |
| format | Article |
| id | doaj-art-ddf27ed846ff45efaebf948a34973f2d |
| institution | DOAJ |
| issn | 2076-2607 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj-art-ddf27ed846ff45efaebf948a34973f2d2025-08-20T02:48:01ZengMDPI AGMicroorganisms2076-26072024-11-011211228210.3390/microorganisms12112282Comparison of QIAstat-Dx and BioFire FilmArray Gastrointestinal Panels in a Pediatric PopulationMohammed Suleiman0Muhammad Iqbal1Patrick Tang2Andrés Pérez-López3Department of Pathology, Sidra Medicine, Doha P.O. Box 26999, QatarDepartment of Pathology, Sidra Medicine, Doha P.O. Box 26999, QatarDepartment of Pathology, Sidra Medicine, Doha P.O. Box 26999, QatarDepartment of Pathology, Sidra Medicine, Doha P.O. Box 26999, QatarAccurate laboratory diagnosis of gastroenteritis is important to ensure that patients receive appropriate treatment and proper isolation precautions. This study evaluated the performance of the QIAGEN QIAstat-Dx gastrointestinal panel (QGP) in comparison to the bioMerieux BioFire FilmArray gastrointestinal panel (BGP) for the detection of gastrointestinal pathogens in 110 pediatric patients being evaluated for gastroenteritis at our hospital. We compared 23 different bacterial, viral, and parasite enteropathogens detected by the QGP against the BGP. The overall positive percent agreement (PPA) for all compared targets was 96.2% and the overall negative percent agreement (NPA) for all compared targets was 99.7%. Our study shows that QIAstat-Dx QGP provides comparable results to the BioFire BGP in our pediatric population. Additionally, the PCR cycle threshold (Ct) value reported by the QGP is potentially a helpful tool in estimating the load of the detected pathogen in stool samples.https://www.mdpi.com/2076-2607/12/11/2282GI panelsyndromic testingQIAstatBioFire |
| spellingShingle | Mohammed Suleiman Muhammad Iqbal Patrick Tang Andrés Pérez-López Comparison of QIAstat-Dx and BioFire FilmArray Gastrointestinal Panels in a Pediatric Population Microorganisms GI panel syndromic testing QIAstat BioFire |
| title | Comparison of QIAstat-Dx and BioFire FilmArray Gastrointestinal Panels in a Pediatric Population |
| title_full | Comparison of QIAstat-Dx and BioFire FilmArray Gastrointestinal Panels in a Pediatric Population |
| title_fullStr | Comparison of QIAstat-Dx and BioFire FilmArray Gastrointestinal Panels in a Pediatric Population |
| title_full_unstemmed | Comparison of QIAstat-Dx and BioFire FilmArray Gastrointestinal Panels in a Pediatric Population |
| title_short | Comparison of QIAstat-Dx and BioFire FilmArray Gastrointestinal Panels in a Pediatric Population |
| title_sort | comparison of qiastat dx and biofire filmarray gastrointestinal panels in a pediatric population |
| topic | GI panel syndromic testing QIAstat BioFire |
| url | https://www.mdpi.com/2076-2607/12/11/2282 |
| work_keys_str_mv | AT mohammedsuleiman comparisonofqiastatdxandbiofirefilmarraygastrointestinalpanelsinapediatricpopulation AT muhammadiqbal comparisonofqiastatdxandbiofirefilmarraygastrointestinalpanelsinapediatricpopulation AT patricktang comparisonofqiastatdxandbiofirefilmarraygastrointestinalpanelsinapediatricpopulation AT andresperezlopez comparisonofqiastatdxandbiofirefilmarraygastrointestinalpanelsinapediatricpopulation |