Exploring the bidirectional causality between neuroticism and frailty: a Mendelian randomization analysis

Exploring the bidirectional causality between neuroticism and frailty: a Mendelian randomization analysis

Abstract Background Epidemiological studies have confirmed the relationship between personality trait neuroticism and physical health. However, the relationship between neuroticism and frailty remains unconfirmed. This study employed a bi-directional two-sample Mendelian randomization (MR) approach...

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Bibliographic Details
Main Authors: Yuhang Xing, Rui Pu, Mengdie Fu, Zhikang Wang, Zhen Wang, Xiaopeng Shang, Guoli Yang, Zhiwei Jiang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Hereditas
Subjects:
Frailty
Mental disorder
Neuroticism
Mendelian randomization
Online Access:https://doi.org/10.1186/s41065-025-00370-2
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