Antiviral efficacy of Andrographis paniculata and andrographolides: A narrative review
The rise of emerging infectious diseases has become notably prominent due to ecological changes and mutations in pathogens. The respiratory illness outbreak caused by the COVID-19 pandemic has spread globally. Natural products contain numerous structures and biological activities, offering ample opt...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-11-01
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| Series: | Asian Pacific Journal of Tropical Biomedicine |
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| Online Access: | https://journals.lww.com/10.4103/apjtb.apjtb_751_23 |
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| _version_ | 1850168597118189568 |
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| author | Kumarappan Chidambaram |
| author_facet | Kumarappan Chidambaram |
| author_sort | Kumarappan Chidambaram |
| collection | DOAJ |
| description | The rise of emerging infectious diseases has become notably prominent due to ecological changes and mutations in pathogens. The respiratory illness outbreak caused by the COVID-19 pandemic has spread globally. Natural products contain numerous structures and biological activities, offering ample options for discovering new antiviral drugs with unique targets and mechanisms. Andrographis paniculata has been utilized in Indian Ayurvedic, Swedish, Traditional Thai, and Chinese medicine to alleviate coughs, colds, and influenza symptoms. Early-stage laboratory studies indicate that this herbal extract may reduce inflammation and fever, and boost the body’s natural defenses against viruses, potentially leading to symptom relief. This review aims to systematically present clinical trial data about antiviral herbal formulations derived from Andrographis paniculata, delineating the antiviral effects of both natural and synthetic derivatives, along with in silico analyses. |
| format | Article |
| id | doaj-art-dde84aa07b6d4742a68a404be189e40d |
| institution | OA Journals |
| issn | 2221-1691 2588-9222 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Pacific Journal of Tropical Biomedicine |
| spelling | doaj-art-dde84aa07b6d4742a68a404be189e40d2025-08-20T02:20:56ZengWolters Kluwer Medknow PublicationsAsian Pacific Journal of Tropical Biomedicine2221-16912588-92222024-11-01141146147610.4103/apjtb.apjtb_751_23Antiviral efficacy of Andrographis paniculata and andrographolides: A narrative reviewKumarappan ChidambaramThe rise of emerging infectious diseases has become notably prominent due to ecological changes and mutations in pathogens. The respiratory illness outbreak caused by the COVID-19 pandemic has spread globally. Natural products contain numerous structures and biological activities, offering ample options for discovering new antiviral drugs with unique targets and mechanisms. Andrographis paniculata has been utilized in Indian Ayurvedic, Swedish, Traditional Thai, and Chinese medicine to alleviate coughs, colds, and influenza symptoms. Early-stage laboratory studies indicate that this herbal extract may reduce inflammation and fever, and boost the body’s natural defenses against viruses, potentially leading to symptom relief. This review aims to systematically present clinical trial data about antiviral herbal formulations derived from Andrographis paniculata, delineating the antiviral effects of both natural and synthetic derivatives, along with in silico analyses.https://journals.lww.com/10.4103/apjtb.apjtb_751_23ayurvedaandrographis paniculataantiviral formulationsandrographolidescovid-19 |
| spellingShingle | Kumarappan Chidambaram Antiviral efficacy of Andrographis paniculata and andrographolides: A narrative review Asian Pacific Journal of Tropical Biomedicine ayurveda andrographis paniculata antiviral formulations andrographolides covid-19 |
| title | Antiviral efficacy of Andrographis paniculata and andrographolides: A narrative review |
| title_full | Antiviral efficacy of Andrographis paniculata and andrographolides: A narrative review |
| title_fullStr | Antiviral efficacy of Andrographis paniculata and andrographolides: A narrative review |
| title_full_unstemmed | Antiviral efficacy of Andrographis paniculata and andrographolides: A narrative review |
| title_short | Antiviral efficacy of Andrographis paniculata and andrographolides: A narrative review |
| title_sort | antiviral efficacy of andrographis paniculata and andrographolides a narrative review |
| topic | ayurveda andrographis paniculata antiviral formulations andrographolides covid-19 |
| url | https://journals.lww.com/10.4103/apjtb.apjtb_751_23 |
| work_keys_str_mv | AT kumarappanchidambaram antiviralefficacyofandrographispaniculataandandrographolidesanarrativereview |