Using the right design controls for acupuncture trials: Methodological rigor and validity in research

Acupuncture treatment can be defined as a medical procedure with an acupuncture needle at acupoints. Establishing suitable control settings is essential, based on the target elements of the acupuncture therapy. In order to properly design a clinical trial or an experiment, a control group must be es...

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Main Authors: Younbyoung Chae, Jun-Hwan Lee, Myeong Soo Lee
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Integrative Medicine Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213422024000064
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author Younbyoung Chae
Jun-Hwan Lee
Myeong Soo Lee
author_facet Younbyoung Chae
Jun-Hwan Lee
Myeong Soo Lee
author_sort Younbyoung Chae
collection DOAJ
description Acupuncture treatment can be defined as a medical procedure with an acupuncture needle at acupoints. Establishing suitable control settings is essential, based on the target elements of the acupuncture therapy. In order to properly design a clinical trial or an experiment, a control group must be established. Here, we overview the significance of the control group and its limitations in acupuncture research. Clinical trials have employed a variety of study designs and controls for acupuncture treatment in order to compare the effects of actual treatments with control groups that include no treatment or treatment as usual, sham acupuncture at true acupoints, real acupuncture at non-acupoints, and sham acupuncture at non-acupoints. In order to determine the point-specificity of acupuncture, real acupuncture at non-acupoints should be taken into consideration, whereas sham acupuncture at the same true acupoints should be used to determine the needling-specific effect of acupuncture. It is crucial to choose the optimum control for acupuncture treatments depending on the study's main goal and to interpret the results in accordance with the research design.
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spelling doaj-art-dde7eb04054c4458bee88a08ba36e9322025-08-20T03:26:04ZengElsevierIntegrative Medicine Research2213-42202024-03-0113110102610.1016/j.imr.2024.101026Using the right design controls for acupuncture trials: Methodological rigor and validity in researchYounbyoung Chae0Jun-Hwan Lee1Myeong Soo Lee2Department of Meridian and Acupoints, College of Korean Medicine, Kyung Hee University, Seoul, Republic of KoreaKM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea; Department of Korean Convergence Medical Science, KIOM School, University of Science & Technology (UST), Daejeon, Republic of Korea; Athinoula A. Martinos Center for Biomedical imaging, Department of Radiology, Massachusettes General Hospital, Harvard Medical School, Boston, MA, USAKM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea; Department of Korean Convergence Medical Science, KIOM School, University of Science & Technology (UST), Daejeon, Republic of Korea; Corresponding author at: KM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.Acupuncture treatment can be defined as a medical procedure with an acupuncture needle at acupoints. Establishing suitable control settings is essential, based on the target elements of the acupuncture therapy. In order to properly design a clinical trial or an experiment, a control group must be established. Here, we overview the significance of the control group and its limitations in acupuncture research. Clinical trials have employed a variety of study designs and controls for acupuncture treatment in order to compare the effects of actual treatments with control groups that include no treatment or treatment as usual, sham acupuncture at true acupoints, real acupuncture at non-acupoints, and sham acupuncture at non-acupoints. In order to determine the point-specificity of acupuncture, real acupuncture at non-acupoints should be taken into consideration, whereas sham acupuncture at the same true acupoints should be used to determine the needling-specific effect of acupuncture. It is crucial to choose the optimum control for acupuncture treatments depending on the study's main goal and to interpret the results in accordance with the research design.http://www.sciencedirect.com/science/article/pii/S2213422024000064AcupunctureControlDesignSham
spellingShingle Younbyoung Chae
Jun-Hwan Lee
Myeong Soo Lee
Using the right design controls for acupuncture trials: Methodological rigor and validity in research
Integrative Medicine Research
Acupuncture
Control
Design
Sham
title Using the right design controls for acupuncture trials: Methodological rigor and validity in research
title_full Using the right design controls for acupuncture trials: Methodological rigor and validity in research
title_fullStr Using the right design controls for acupuncture trials: Methodological rigor and validity in research
title_full_unstemmed Using the right design controls for acupuncture trials: Methodological rigor and validity in research
title_short Using the right design controls for acupuncture trials: Methodological rigor and validity in research
title_sort using the right design controls for acupuncture trials methodological rigor and validity in research
topic Acupuncture
Control
Design
Sham
url http://www.sciencedirect.com/science/article/pii/S2213422024000064
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