Immune responses following DNA vaccination by needle-free injection against Burkholderia pseudomallei hemolysin co-regulated protein 1

Immune responses following DNA vaccination by needle-free injection against Burkholderia pseudomallei hemolysin co-regulated protein 1

Burkholderia pseudomallei is a facultative intracellular bacterium found in soil, which causes melioidosis, a disease with diverse symptomatology. B. pseudomallei is an emerging threat in the United States based on recent environmental samples and case reports. Acute infection is 10%–40% fatal depen...

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Bibliographic Details
Main Authors: Michael L. Davies, Sergei S. Biryukov, Christopher P. Klimko, Jennifer L. Dankmeyer, Nathaniel O. Rill, Melissa Hunter, Christopher T. Braun, Deven W. Patrick, Tyrique D. David, Steven A. Kwilas, Carlos I. Rodriguez, Brian A. Smith, Ju Qiu, Jay W. Hooper, Christopher K. Cote
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
melioidosis
Burkholderia pseudomallei
vaccines
DNA vaccines
needle-free injection
mice
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1612540/full
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