Distinct oligomeric assemblies of STING induced by non-nucleotide agonists
Abstract STING plays essential roles coordinating innate immune responses to processes that range from pathogenic infection to genomic instability. Its adaptor function is activated by cyclic dinucleotide (CDN) secondary messengers originating from self (2’3’-cGAMP) or bacterial sources (3’3’-CDNs)....
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| Main Authors: | Anant Gharpure, Ariana Sulpizio, Johannes R. Loeffler, Monica L. Fernández-Quintero, Andy S. Tran, Luke L. Lairson, Andrew B. Ward |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-58641-5 |
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