NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND ESSENTIAL OILS IN THE TREATMENT OF GUM AND MUCOSAL DISEASES
Gum and mucosal diseases are characterized by inflammatory processes that require effective treatment to reduce pain and prevent complications. Non-steroidal anti-inflammatory drugs (NSAIDs) are the main therapeutic solution, acting by inhibiting cyclooxygenase and reducing the synthesis of prostagl...
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| Format: | Article |
| Language: | English |
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Romanian Society of Oral Rehabilitation
2025-03-01
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| Series: | Romanian Journal of Oral Rehabilitation |
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| Online Access: | https://rjor.ro/non-steroidal-anti-inflammatory-drugs-and-essential-oils-in-the-treatment-of-gum-and-mucosal-diseases/ |
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| author | Denisa Marin Batir Irina Adriana Beuran Gabriel Valeriu Popa Anamaria Zaharescu Daniela Mihalache |
| author_facet | Denisa Marin Batir Irina Adriana Beuran Gabriel Valeriu Popa Anamaria Zaharescu Daniela Mihalache |
| author_sort | Denisa Marin Batir |
| collection | DOAJ |
| description | Gum and mucosal diseases are characterized by inflammatory processes that require effective treatment to reduce pain and prevent complications. Non-steroidal anti-inflammatory drugs (NSAIDs) are the main therapeutic solution, acting by inhibiting cyclooxygenase and reducing the synthesis of prostaglandins. However, their prolonged use can cause gastrointestinal and renal adverse effects. In this context, essential oils have gained attention due to their anti-inflammatory, antimicrobial and antioxidant properties. Compounds such as eugenol, thymol and carvacrol have demonstrated effectiveness in reducing inflammation and oxidative stress, having a superior safety profile. The comparison of the two therapeutic classes highlights the rapid effectiveness of NSAIDs in acute inflammation, while essential oils are more suitable for adjuvant therapies and chronic inflammation. Future research should explore combined formulations that maximize the benefits of both types of treatment while reducing adverse effects. The development of optimized products, such as gels and mouthwashes with NSAIDs and essential oils, can be an effective strategy for the management of gum and mucosal diseases. |
| format | Article |
| id | doaj-art-ddd4abd660424d13b263b93dae3c4107 |
| institution | Kabale University |
| issn | 2066-7000 2601-4661 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Romanian Society of Oral Rehabilitation |
| record_format | Article |
| series | Romanian Journal of Oral Rehabilitation |
| spelling | doaj-art-ddd4abd660424d13b263b93dae3c41072025-08-20T03:26:38ZengRomanian Society of Oral RehabilitationRomanian Journal of Oral Rehabilitation2066-70002601-46612025-03-0117186988210.62610/RJOR.2025.1.17.84NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND ESSENTIAL OILS IN THE TREATMENT OF GUM AND MUCOSAL DISEASESDenisa Marin Batir0Irina Adriana Beuran1Gabriel Valeriu Popa2Anamaria Zaharescu3Daniela Mihalache4Faculty of Medicine and Pharmacy, University “Dunarea de Jos” Galati, RomaniaFaculty of Medicine and Pharmacy, University “Carol Davila” Bucuresti , RomaniaFaculty of Medicine and Pharmacy, University “Dunarea de Jos” Galati, RomaniaFaculty of Medicine and Pharmacy, University “Dunarea de Jos” Galati, RomaniaFaculty of Medicine and Pharmacy, University “Dunarea de Jos” Galati, RomaniaGum and mucosal diseases are characterized by inflammatory processes that require effective treatment to reduce pain and prevent complications. Non-steroidal anti-inflammatory drugs (NSAIDs) are the main therapeutic solution, acting by inhibiting cyclooxygenase and reducing the synthesis of prostaglandins. However, their prolonged use can cause gastrointestinal and renal adverse effects. In this context, essential oils have gained attention due to their anti-inflammatory, antimicrobial and antioxidant properties. Compounds such as eugenol, thymol and carvacrol have demonstrated effectiveness in reducing inflammation and oxidative stress, having a superior safety profile. The comparison of the two therapeutic classes highlights the rapid effectiveness of NSAIDs in acute inflammation, while essential oils are more suitable for adjuvant therapies and chronic inflammation. Future research should explore combined formulations that maximize the benefits of both types of treatment while reducing adverse effects. The development of optimized products, such as gels and mouthwashes with NSAIDs and essential oils, can be an effective strategy for the management of gum and mucosal diseases.https://rjor.ro/non-steroidal-anti-inflammatory-drugs-and-essential-oils-in-the-treatment-of-gum-and-mucosal-diseases/nsaidsessential oilsoral inflammationgingivitisperiodontitiseugenoladjuvant treatment |
| spellingShingle | Denisa Marin Batir Irina Adriana Beuran Gabriel Valeriu Popa Anamaria Zaharescu Daniela Mihalache NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND ESSENTIAL OILS IN THE TREATMENT OF GUM AND MUCOSAL DISEASES Romanian Journal of Oral Rehabilitation nsaids essential oils oral inflammation gingivitis periodontitis eugenol adjuvant treatment |
| title | NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND ESSENTIAL OILS IN THE TREATMENT OF GUM AND MUCOSAL DISEASES |
| title_full | NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND ESSENTIAL OILS IN THE TREATMENT OF GUM AND MUCOSAL DISEASES |
| title_fullStr | NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND ESSENTIAL OILS IN THE TREATMENT OF GUM AND MUCOSAL DISEASES |
| title_full_unstemmed | NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND ESSENTIAL OILS IN THE TREATMENT OF GUM AND MUCOSAL DISEASES |
| title_short | NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND ESSENTIAL OILS IN THE TREATMENT OF GUM AND MUCOSAL DISEASES |
| title_sort | non steroidal anti inflammatory drugs and essential oils in the treatment of gum and mucosal diseases |
| topic | nsaids essential oils oral inflammation gingivitis periodontitis eugenol adjuvant treatment |
| url | https://rjor.ro/non-steroidal-anti-inflammatory-drugs-and-essential-oils-in-the-treatment-of-gum-and-mucosal-diseases/ |
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