“Bilateral Capnocytophaga Canimorsus Periprosthetic Joint Infections in an Immunocompromised Patient: A Case Report and Literature Review”

A 63-year-old dog owner with bilateral total knee arthroplasties developed periprosthetic joint infections bilaterally due to Capnocytophaga canimorsus (C canimorsus), a bacterium commonly found in the saliva of dogs and cats. Aerobic and anaerobic cultures from explant surgery were negative; howeve...

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Bibliographic Details
Main Authors: Philomena Burger, BA, Mina Botros, MD, Katelyn S. Quartuccio, PharmD, BCIDP, Sonal S. Munsiff, MD, Thomas Myers, MD, MPT
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Arthroplasty Today
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352344125000512
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Summary:A 63-year-old dog owner with bilateral total knee arthroplasties developed periprosthetic joint infections bilaterally due to Capnocytophaga canimorsus (C canimorsus), a bacterium commonly found in the saliva of dogs and cats. Aerobic and anaerobic cultures from explant surgery were negative; however, bacterial 16S polymerase chain reaction followed by sequencing of the amplified product identified C canimorsus in both knees. Treatment was successful with bilateral explant, antibiotic spacers, intravenous antibiotics, and reimplantation. C canimorsus is a rare cause of prostheses infections. As total knee arthroplasty prevalence increases, infections will also increase. Treatment is best provided with collaboration among orthopaedic surgeons, infectious disease specialists, and pharmacists.
ISSN:2352-3441