Risk factors for lung parenchyma hemorrhage and hemoptysis during computed tomography‐guided microwave ablation in patients with stage I non‐small cell lung cancer: A bicentric retrospective study
Abstract Objectives This study aimed to identify the risk factors for lung parenchyma hemorrhage and hemoptysis during computed tomography‐guided microwave ablation (MWA) in patients with stage I non‐small cell lung cancer (NSCLC). Methods A total of 417 patients from two medical centers were includ...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-11-01
|
| Series: | Thoracic Cancer |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/1759-7714.15466 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850129112500273152 |
|---|---|
| author | Jingshuo Li Ziqi Zhang Yuxian Chen Chunhai Li Zhigang Wei Haipeng Jia |
| author_facet | Jingshuo Li Ziqi Zhang Yuxian Chen Chunhai Li Zhigang Wei Haipeng Jia |
| author_sort | Jingshuo Li |
| collection | DOAJ |
| description | Abstract Objectives This study aimed to identify the risk factors for lung parenchyma hemorrhage and hemoptysis during computed tomography‐guided microwave ablation (MWA) in patients with stage I non‐small cell lung cancer (NSCLC). Methods A total of 417 patients from two medical centers were included, of whom 353 were from center 1 and 64 were from center 2. The risk factors for lung parenchyma hemorrhage and hemoptysis were selected by univariable and multivariable logistic analyses in the center 1 dataset. The selected risk factors were validated in the center 2 dataset. Results The risk factors for lung parenchyma hemorrhage during MWA were focal blood supplies (odds ratio [OR], 2.602; 95% confidence interval [CI], 1.609–4.210; p < 0.001), near vessels larger than 2 mm (OR, 4.145; 95% CI, 1.963–8.755; p < 0.001), and traversing vessels in the track of ablation (OR, 2.961; 95% CI, 1.492–5.874; p = 0.002). The risk factors for hemoptysis were lung parenchyma hemorrhage (OR, 34.165; 95% CI, 12.255–95.247; p < 0.001), needle track traversing the lung parenchyma by >25 mm (OR, 4.494; 95% CI, 1.833–11.018; p = 0.001), and traversing vessels in the track of ablation (OR, 5.402; 95% CI, 2.269–12.865; p < 0.001). Conclusions Focal blood supplies, near vessels larger than 2 mm, and traversing vessels in the track of ablation were independent risk factors for lung parenchyma hemorrhage during MWA. Lung parenchyma hemorrhage, needle track traversing the lung parenchyma by >25 mm, and traversing vessels in the track of ablation were independent risk factors for hemoptysis during MWA. |
| format | Article |
| id | doaj-art-ddd2976df3f54120be9011e038bb55d3 |
| institution | OA Journals |
| issn | 1759-7706 1759-7714 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | Thoracic Cancer |
| spelling | doaj-art-ddd2976df3f54120be9011e038bb55d32025-08-20T02:33:06ZengWileyThoracic Cancer1759-77061759-77142024-11-0115332386239410.1111/1759-7714.15466Risk factors for lung parenchyma hemorrhage and hemoptysis during computed tomography‐guided microwave ablation in patients with stage I non‐small cell lung cancer: A bicentric retrospective studyJingshuo Li0Ziqi Zhang1Yuxian Chen2Chunhai Li3Zhigang Wei4Haipeng Jia5Department of Radiology Qilu Hospital of Shandong University Jinan ChinaDepartment of Radiology Qilu Hospital of Shandong University Jinan ChinaCheeloo College of Medicine Shandong University Jinan ChinaDepartment of Radiology Qilu Hospital of Shandong University Jinan ChinaDepartment of Oncology Shandong Provincial Qianfoshan Hospital Jinan ChinaDepartment of Radiology Qilu Hospital of Shandong University Jinan ChinaAbstract Objectives This study aimed to identify the risk factors for lung parenchyma hemorrhage and hemoptysis during computed tomography‐guided microwave ablation (MWA) in patients with stage I non‐small cell lung cancer (NSCLC). Methods A total of 417 patients from two medical centers were included, of whom 353 were from center 1 and 64 were from center 2. The risk factors for lung parenchyma hemorrhage and hemoptysis were selected by univariable and multivariable logistic analyses in the center 1 dataset. The selected risk factors were validated in the center 2 dataset. Results The risk factors for lung parenchyma hemorrhage during MWA were focal blood supplies (odds ratio [OR], 2.602; 95% confidence interval [CI], 1.609–4.210; p < 0.001), near vessels larger than 2 mm (OR, 4.145; 95% CI, 1.963–8.755; p < 0.001), and traversing vessels in the track of ablation (OR, 2.961; 95% CI, 1.492–5.874; p = 0.002). The risk factors for hemoptysis were lung parenchyma hemorrhage (OR, 34.165; 95% CI, 12.255–95.247; p < 0.001), needle track traversing the lung parenchyma by >25 mm (OR, 4.494; 95% CI, 1.833–11.018; p = 0.001), and traversing vessels in the track of ablation (OR, 5.402; 95% CI, 2.269–12.865; p < 0.001). Conclusions Focal blood supplies, near vessels larger than 2 mm, and traversing vessels in the track of ablation were independent risk factors for lung parenchyma hemorrhage during MWA. Lung parenchyma hemorrhage, needle track traversing the lung parenchyma by >25 mm, and traversing vessels in the track of ablation were independent risk factors for hemoptysis during MWA.https://doi.org/10.1111/1759-7714.15466complicationcomputed tomographyhemorrhagemicrowave ablationpulmonary malignancy |
| spellingShingle | Jingshuo Li Ziqi Zhang Yuxian Chen Chunhai Li Zhigang Wei Haipeng Jia Risk factors for lung parenchyma hemorrhage and hemoptysis during computed tomography‐guided microwave ablation in patients with stage I non‐small cell lung cancer: A bicentric retrospective study Thoracic Cancer complication computed tomography hemorrhage microwave ablation pulmonary malignancy |
| title | Risk factors for lung parenchyma hemorrhage and hemoptysis during computed tomography‐guided microwave ablation in patients with stage I non‐small cell lung cancer: A bicentric retrospective study |
| title_full | Risk factors for lung parenchyma hemorrhage and hemoptysis during computed tomography‐guided microwave ablation in patients with stage I non‐small cell lung cancer: A bicentric retrospective study |
| title_fullStr | Risk factors for lung parenchyma hemorrhage and hemoptysis during computed tomography‐guided microwave ablation in patients with stage I non‐small cell lung cancer: A bicentric retrospective study |
| title_full_unstemmed | Risk factors for lung parenchyma hemorrhage and hemoptysis during computed tomography‐guided microwave ablation in patients with stage I non‐small cell lung cancer: A bicentric retrospective study |
| title_short | Risk factors for lung parenchyma hemorrhage and hemoptysis during computed tomography‐guided microwave ablation in patients with stage I non‐small cell lung cancer: A bicentric retrospective study |
| title_sort | risk factors for lung parenchyma hemorrhage and hemoptysis during computed tomography guided microwave ablation in patients with stage i non small cell lung cancer a bicentric retrospective study |
| topic | complication computed tomography hemorrhage microwave ablation pulmonary malignancy |
| url | https://doi.org/10.1111/1759-7714.15466 |
| work_keys_str_mv | AT jingshuoli riskfactorsforlungparenchymahemorrhageandhemoptysisduringcomputedtomographyguidedmicrowaveablationinpatientswithstageinonsmallcelllungcancerabicentricretrospectivestudy AT ziqizhang riskfactorsforlungparenchymahemorrhageandhemoptysisduringcomputedtomographyguidedmicrowaveablationinpatientswithstageinonsmallcelllungcancerabicentricretrospectivestudy AT yuxianchen riskfactorsforlungparenchymahemorrhageandhemoptysisduringcomputedtomographyguidedmicrowaveablationinpatientswithstageinonsmallcelllungcancerabicentricretrospectivestudy AT chunhaili riskfactorsforlungparenchymahemorrhageandhemoptysisduringcomputedtomographyguidedmicrowaveablationinpatientswithstageinonsmallcelllungcancerabicentricretrospectivestudy AT zhigangwei riskfactorsforlungparenchymahemorrhageandhemoptysisduringcomputedtomographyguidedmicrowaveablationinpatientswithstageinonsmallcelllungcancerabicentricretrospectivestudy AT haipengjia riskfactorsforlungparenchymahemorrhageandhemoptysisduringcomputedtomographyguidedmicrowaveablationinpatientswithstageinonsmallcelllungcancerabicentricretrospectivestudy |