Invasive Nontyphoidal Salmonella Infection in a Patient with Early-Stage Chronic Lymphocytic Leukemia
We describe a case of a 72-year-old man with early-stage chronic lymphocytic leukemia (CLL) who presented with invasive nontyphoidal Salmonella (iNTS) infection, necrotizing pneumonia, and chronic infection of a hilar lymph node. Infection is a major cause of death in patients with CLL. Though few c...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2017/9091276 |
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| author | Deepika Slawek Yanina Dubrovskaya Eddie Louie |
| author_facet | Deepika Slawek Yanina Dubrovskaya Eddie Louie |
| author_sort | Deepika Slawek |
| collection | DOAJ |
| description | We describe a case of a 72-year-old man with early-stage chronic lymphocytic leukemia (CLL) who presented with invasive nontyphoidal Salmonella (iNTS) infection, necrotizing pneumonia, and chronic infection of a hilar lymph node. Infection is a major cause of death in patients with CLL. Though few cases of iNTS infection associated with CLL have been described in the literature, to our knowledge this is the first reported case of iNTS-associated necrotizing pneumonia. Immunocompromised state in patients, even with early-stage CLL, likely predisposes them to invasive infection with intracellular organisms, such as Salmonella spp. In this case, successful treatment was achieved with prolonged course of intravenous followed by oral antibiotics without any surgical removal of infected focus. |
| format | Article |
| id | doaj-art-ddc9e63e02e142a281bebd035499d0f7 |
| institution | OA Journals |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-ddc9e63e02e142a281bebd035499d0f72025-08-20T02:21:33ZengWileyCase Reports in Infectious Diseases2090-66252090-66332017-01-01201710.1155/2017/90912769091276Invasive Nontyphoidal Salmonella Infection in a Patient with Early-Stage Chronic Lymphocytic LeukemiaDeepika Slawek0Yanina Dubrovskaya1Eddie Louie2Division of Infectious Diseases, NYU School of Medicine, 550 First Avenue NBV 16 South 5-13, New York, NY 10016, USADivision of Infectious Diseases, NYU School of Medicine, 550 First Avenue NBV 16 South 5-13, New York, NY 10016, USADivision of Infectious Diseases, NYU School of Medicine, 550 First Avenue NBV 16 South 5-13, New York, NY 10016, USAWe describe a case of a 72-year-old man with early-stage chronic lymphocytic leukemia (CLL) who presented with invasive nontyphoidal Salmonella (iNTS) infection, necrotizing pneumonia, and chronic infection of a hilar lymph node. Infection is a major cause of death in patients with CLL. Though few cases of iNTS infection associated with CLL have been described in the literature, to our knowledge this is the first reported case of iNTS-associated necrotizing pneumonia. Immunocompromised state in patients, even with early-stage CLL, likely predisposes them to invasive infection with intracellular organisms, such as Salmonella spp. In this case, successful treatment was achieved with prolonged course of intravenous followed by oral antibiotics without any surgical removal of infected focus.http://dx.doi.org/10.1155/2017/9091276 |
| spellingShingle | Deepika Slawek Yanina Dubrovskaya Eddie Louie Invasive Nontyphoidal Salmonella Infection in a Patient with Early-Stage Chronic Lymphocytic Leukemia Case Reports in Infectious Diseases |
| title | Invasive Nontyphoidal Salmonella Infection in a Patient with Early-Stage Chronic Lymphocytic Leukemia |
| title_full | Invasive Nontyphoidal Salmonella Infection in a Patient with Early-Stage Chronic Lymphocytic Leukemia |
| title_fullStr | Invasive Nontyphoidal Salmonella Infection in a Patient with Early-Stage Chronic Lymphocytic Leukemia |
| title_full_unstemmed | Invasive Nontyphoidal Salmonella Infection in a Patient with Early-Stage Chronic Lymphocytic Leukemia |
| title_short | Invasive Nontyphoidal Salmonella Infection in a Patient with Early-Stage Chronic Lymphocytic Leukemia |
| title_sort | invasive nontyphoidal salmonella infection in a patient with early stage chronic lymphocytic leukemia |
| url | http://dx.doi.org/10.1155/2017/9091276 |
| work_keys_str_mv | AT deepikaslawek invasivenontyphoidalsalmonellainfectioninapatientwithearlystagechroniclymphocyticleukemia AT yaninadubrovskaya invasivenontyphoidalsalmonellainfectioninapatientwithearlystagechroniclymphocyticleukemia AT eddielouie invasivenontyphoidalsalmonellainfectioninapatientwithearlystagechroniclymphocyticleukemia |