Blue Light Emitting Diode Suppresses Sarcoma Cell Proliferation via the Endogenous Apoptotic Pathway Without Damaging Normal Cells

Blue Light Emitting Diode Suppresses Sarcoma Cell Proliferation via the Endogenous Apoptotic Pathway Without Damaging Normal Cells

ABSTRACT Background The development of novel therapies for sarcoma is urgently required because most sarcomas are refractory to adjuvant therapy and the treatment options are limited. Although antitumor effects of blue light (BL) have been reported for several malignant tumors, its impact on various...

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Bibliographic Details
Main Authors: Shinji Kawaguchi, Toshihiko Nishisho, Shunichi Toki, Makoto Takeuchi, Shunsuke Tamaki, Koichi Sairyo
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Cancer Medicine
Subjects:
blue light
endogenous apoptosis
normal human dermal cell
osteosarcoma
reactive oxygen species
soft tissue sarcoma
Online Access:https://doi.org/10.1002/cam4.70770
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