Does side matter? Deciphering mechanisms that underpin side-dependent pathogenesis and therapy response in colorectal cancer

Abstract Colorectal cancer (CRC) is stratified by heterogeneity between disease sites, with proximal right-sided CRC (RCRC) multifactorial in its distinction from distal left-sided CRC (LCRC). Notably, right-sided tumors are associated with aggressive disease characteristics which culminate in poor...

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Bibliographic Details
Main Authors: Harrison J. Boka, Rebekah M. Engel, Christine Georges, Paul J. McMurrick, Helen E. Abud
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Molecular Cancer
Online Access:https://doi.org/10.1186/s12943-025-02327-5
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