Comparison of molecular genetic methods of detection of mutations in the CALR gene in myeloproliferative disorders

Comparison of molecular genetic methods of detection of mutations in the CALR gene in myeloproliferative disorders

Molecular genetic detection of CALR gene somatic mutations is required for myeloproliferative neoplasms diagnosis and treatment according to the novel WHO clinical recommendations. CALR mutations are found in approximately 25–35 % cases of essential thrombocythemia and primary myelofibrosis and they...

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Main Authors: L. A. Kesaeva, A. Yu. Bulanov, Yu. P. Finashutina, V. V. Tikhonova, O. N. Solopova, E. N. Misyurina, N. N. Kasatkina, N. A. Lyzhko, V. A. Misyurin, A. A. Turba, A. A. Solodovnik, I. N. Soldatova, A. V. Misyurin
Format: Article
Language:Russian
Published: ABV-press 2019-07-01
Series:Успехи молекулярной онкологии
Subjects:
calr
polycythemia vera
essential thrombocythemia
primary myelofibrosis
Online Access:https://umo.abvpress.ru/jour/article/view/218
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