HAT1/HDAC2 mediated ACSL4 acetylation confers radiosensitivity by inducing ferroptosis in nasopharyngeal carcinoma

Abstract Protein acetylation modification plays important roles in various aspects of tumor progression. Ferroptosis driven by lethal lipid peroxidation is closely related to tumor development. Targeting ferroptosis has become a promising strategy. However, the crosstalk between protein acetylation...

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Bibliographic Details
Main Authors: Peijun Zhou, Xingzhi Peng, Kun zhang, Jin Cheng, Min Tang, Lin Shen, Qin Zhou, Dan Li, Lifang Yang
Format: Article
Language:English
Published: Nature Publishing Group 2025-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07477-4
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