The role of glutamine synthetase expression and cystine/glutamate transporter (SLC7A11, xCT) in epilepsy pathogenesis of patients with supratentorial brain gliomas

The role of glutamine synthetase expression and cystine/glutamate transporter (SLC7A11, xCT) in epilepsy pathogenesis of patients with supratentorial brain gliomas

Background. Epileptic seizures represent one of the leading clinical manifestations of glial brain tumors that develop on average in 51% of cases. In gliomas, epileptogenesis is quite complex and multifactorial.Objective: to study a role of the expressed glutamine synthetase enzyme, as well as cysti...

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Bibliographic Details
Main Authors: M. Yu. Prokudin, B. V. Martynov, A. I. Yakovenko, I. V. Litvinenko, V. Yu. Lobzin, D. V. Svistov, V. S. Chirskiy, K. A. Chemodakova, O. А. Klitsenko
Format: Article
Language:Russian
Published: IRBIS LLC 2022-07-01
Series:Эпилепсия и пароксизмальные состояния
Subjects:
glioma
epilepsy
glutamine synthetase
cystine/glutamate transporter (slc7a11
xct)
epilepsy pathogenesis
Online Access:https://www.epilepsia.su/jour/article/view/795
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