Estimation of Cardiovascular Risk by Framingham Score in a Cross-sectional Sample of Schizophrenia Inpatients
The lifespan of schizophrenia (SCZ) patients is considered 25 years shorter compared to the general population, primarily due to cardiovascular (CV) disease. This study aims to assess the CV profile of the SCZ inpatients from Psychiatry Clinic I and II of Cluj-Napoca between 2018-2019. Methods: The...
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Bucharest College of Physicians
2023-01-01
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| Series: | Modern Medicine |
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| Online Access: | https://medicinamoderna.ro/wp-content/uploads/2023/06/Estimation-of-Cardiovascular-Risk-by-Framingham-Score-in-a-Cross-sectional-Sample-of-Schizophrenia-Inpatients.pdf |
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| author | Cosmin-Ioan MOGA Ioana Valentina MICLUTIA Catalina Angela CRISAN Mihaela FADYGAS-STANCULETE |
| author_facet | Cosmin-Ioan MOGA Ioana Valentina MICLUTIA Catalina Angela CRISAN Mihaela FADYGAS-STANCULETE |
| author_sort | Cosmin-Ioan MOGA |
| collection | DOAJ |
| description | The lifespan of schizophrenia (SCZ) patients is considered 25 years shorter compared to the general population, primarily due to cardiovascular (CV) disease. This study aims to assess the CV profile of the SCZ inpatients from Psychiatry Clinic I and II of Cluj-Napoca between 2018-2019. Methods: The following indicators were documented from interview and laboratory data: arterial hypertension (AHT), smoking, dyslipidemia, obesity, metabolic syndrome (MS), medication adherence (MA), Framingham score (FS), and CV diagnosis (CVd). The sample was separated into two groups based on FS and CV diagnosis: high-risk/CVd and medium/low-risk. Results: 50 SCZ patients were included in the study. 58% had AHT and 10% were prediagnosed, 90% had lipids perturbations of which 26.7% were prediagnosed, 66 % met the criteria for MS from which one prediagnosis, 12% had a CVd and the average FS was 12.7% corresponding to intermediate risk category. MA subjects had a lower risk to be in the high risk/CVd group (OR=1/0.22, p=0.02) and no association was found for the gender-CV risk categories (p=0.08). Conclusion: 1. The known CV risk factors are underdiagnosed in SCZ patients 2. SCZ might attenuate the gender CV risk stratification; and 3. MA might decrease the CV risk in SCZ. |
| format | Article |
| id | doaj-art-ddab2f3188f345f396bf08aec0d32feb |
| institution | OA Journals |
| issn | 1223-0472 2360-2473 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Bucharest College of Physicians |
| record_format | Article |
| series | Modern Medicine |
| spelling | doaj-art-ddab2f3188f345f396bf08aec0d32feb2025-08-20T01:55:45ZengBucharest College of PhysiciansModern Medicine1223-04722360-24732023-01-01302101110https://doi.org/10.31689/rmm.2023.30.2.101Estimation of Cardiovascular Risk by Framingham Score in a Cross-sectional Sample of Schizophrenia InpatientsCosmin-Ioan MOGA0https://orcid.org/0000-0003-2521-1421Ioana Valentina MICLUTIA1https://orcid.org/0000-0003-2478-0876Catalina Angela CRISAN2Mihaela FADYGAS-STANCULETE3Department of Psychiatry, Faculty of Medicine, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Psychiatry, Faculty of Medicine, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Psychiatry, Faculty of Medicine, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Psychiatry, Faculty of Medicine, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, RomaniaThe lifespan of schizophrenia (SCZ) patients is considered 25 years shorter compared to the general population, primarily due to cardiovascular (CV) disease. This study aims to assess the CV profile of the SCZ inpatients from Psychiatry Clinic I and II of Cluj-Napoca between 2018-2019. Methods: The following indicators were documented from interview and laboratory data: arterial hypertension (AHT), smoking, dyslipidemia, obesity, metabolic syndrome (MS), medication adherence (MA), Framingham score (FS), and CV diagnosis (CVd). The sample was separated into two groups based on FS and CV diagnosis: high-risk/CVd and medium/low-risk. Results: 50 SCZ patients were included in the study. 58% had AHT and 10% were prediagnosed, 90% had lipids perturbations of which 26.7% were prediagnosed, 66 % met the criteria for MS from which one prediagnosis, 12% had a CVd and the average FS was 12.7% corresponding to intermediate risk category. MA subjects had a lower risk to be in the high risk/CVd group (OR=1/0.22, p=0.02) and no association was found for the gender-CV risk categories (p=0.08). Conclusion: 1. The known CV risk factors are underdiagnosed in SCZ patients 2. SCZ might attenuate the gender CV risk stratification; and 3. MA might decrease the CV risk in SCZ.https://medicinamoderna.ro/wp-content/uploads/2023/06/Estimation-of-Cardiovascular-Risk-by-Framingham-Score-in-a-Cross-sectional-Sample-of-Schizophrenia-Inpatients.pdfschizophreniacardiovascularframingham scorecomorbiditiesmetabolic syndrome |
| spellingShingle | Cosmin-Ioan MOGA Ioana Valentina MICLUTIA Catalina Angela CRISAN Mihaela FADYGAS-STANCULETE Estimation of Cardiovascular Risk by Framingham Score in a Cross-sectional Sample of Schizophrenia Inpatients Modern Medicine schizophrenia cardiovascular framingham score comorbidities metabolic syndrome |
| title | Estimation of Cardiovascular Risk by Framingham Score in a Cross-sectional Sample of Schizophrenia Inpatients |
| title_full | Estimation of Cardiovascular Risk by Framingham Score in a Cross-sectional Sample of Schizophrenia Inpatients |
| title_fullStr | Estimation of Cardiovascular Risk by Framingham Score in a Cross-sectional Sample of Schizophrenia Inpatients |
| title_full_unstemmed | Estimation of Cardiovascular Risk by Framingham Score in a Cross-sectional Sample of Schizophrenia Inpatients |
| title_short | Estimation of Cardiovascular Risk by Framingham Score in a Cross-sectional Sample of Schizophrenia Inpatients |
| title_sort | estimation of cardiovascular risk by framingham score in a cross sectional sample of schizophrenia inpatients |
| topic | schizophrenia cardiovascular framingham score comorbidities metabolic syndrome |
| url | https://medicinamoderna.ro/wp-content/uploads/2023/06/Estimation-of-Cardiovascular-Risk-by-Framingham-Score-in-a-Cross-sectional-Sample-of-Schizophrenia-Inpatients.pdf |
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