Iron-binding property of lactoferrin in the case of inflammation

Lactoferrin (Lf) is a biologically important molecule, that accomplishes a number of useful functions in an organism. Lf can be situated in conditions associated with enrichment of reactive halogen species (asthma, infectious disease, heart-disease etс.). It was shown using spectrophotometric and fl...

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Main Authors: M. S. Terekhova, I. V. Gorudko, D. V. Grigorieva, I. V. Semak, A. V. Sokolov, O. M. Panasenko, S. N. Cherenkevich
Format: Article
Language:Russian
Published: Educational institution «Belarusian State University of Informatics and Radioelectronics» 2019-06-01
Series:Doklady Belorusskogo gosudarstvennogo universiteta informatiki i radioèlektroniki
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Online Access:https://doklady.bsuir.by/jour/article/view/1046
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author M. S. Terekhova
I. V. Gorudko
D. V. Grigorieva
I. V. Semak
A. V. Sokolov
O. M. Panasenko
S. N. Cherenkevich
author_facet M. S. Terekhova
I. V. Gorudko
D. V. Grigorieva
I. V. Semak
A. V. Sokolov
O. M. Panasenko
S. N. Cherenkevich
author_sort M. S. Terekhova
collection DOAJ
description Lactoferrin (Lf) is a biologically important molecule, that accomplishes a number of useful functions in an organism. Lf can be situated in conditions associated with enrichment of reactive halogen species (asthma, infectious disease, heart-disease etс.). It was shown using spectrophotometric and fluorescence methods that HOCl and particularly HOBr lead to significant destruction of Trp residues and iron-binding capacity of Lf.
format Article
id doaj-art-ddab0bb6b2324921bcae696360d2bfe8
institution Kabale University
issn 1729-7648
language Russian
publishDate 2019-06-01
publisher Educational institution «Belarusian State University of Informatics and Radioelectronics»
record_format Article
series Doklady Belorusskogo gosudarstvennogo universiteta informatiki i radioèlektroniki
spelling doaj-art-ddab0bb6b2324921bcae696360d2bfe82025-08-20T03:59:27ZrusEducational institution «Belarusian State University of Informatics and Radioelectronics»Doklady Belorusskogo gosudarstvennogo universiteta informatiki i radioèlektroniki1729-76482019-06-010780841045Iron-binding property of lactoferrin in the case of inflammationM. S. Terekhova0I. V. Gorudko1D. V. Grigorieva2I. V. Semak3A. V. Sokolov4O. M. Panasenko5S. N. Cherenkevich6Белорусский государственный университет, Республика БеларусьБелорусский государственный университет, Республика БеларусьБелорусский государственный университет, Республика БеларусьБелорусский государственный университет, Республика БеларусьФГБНУ «Институт экспериментальной медицины», Российская ФедерацияФедеральный научно-клинический центр физико-химической медицины ФМБА России, Российская ФедерацияБелорусский государственный университет, Республика БеларусьLactoferrin (Lf) is a biologically important molecule, that accomplishes a number of useful functions in an organism. Lf can be situated in conditions associated with enrichment of reactive halogen species (asthma, infectious disease, heart-disease etс.). It was shown using spectrophotometric and fluorescence methods that HOCl and particularly HOBr lead to significant destruction of Trp residues and iron-binding capacity of Lf.https://doklady.bsuir.by/jour/article/view/1046hoclhobrlactoferrintryptophaniron binding propertyhoclhobr
spellingShingle M. S. Terekhova
I. V. Gorudko
D. V. Grigorieva
I. V. Semak
A. V. Sokolov
O. M. Panasenko
S. N. Cherenkevich
Iron-binding property of lactoferrin in the case of inflammation
Doklady Belorusskogo gosudarstvennogo universiteta informatiki i radioèlektroniki
hocl
hobr
lactoferrin
tryptophan
iron binding property
hocl
hobr
title Iron-binding property of lactoferrin in the case of inflammation
title_full Iron-binding property of lactoferrin in the case of inflammation
title_fullStr Iron-binding property of lactoferrin in the case of inflammation
title_full_unstemmed Iron-binding property of lactoferrin in the case of inflammation
title_short Iron-binding property of lactoferrin in the case of inflammation
title_sort iron binding property of lactoferrin in the case of inflammation
topic hocl
hobr
lactoferrin
tryptophan
iron binding property
hocl
hobr
url https://doklady.bsuir.by/jour/article/view/1046
work_keys_str_mv AT msterekhova ironbindingpropertyoflactoferrininthecaseofinflammation
AT ivgorudko ironbindingpropertyoflactoferrininthecaseofinflammation
AT dvgrigorieva ironbindingpropertyoflactoferrininthecaseofinflammation
AT ivsemak ironbindingpropertyoflactoferrininthecaseofinflammation
AT avsokolov ironbindingpropertyoflactoferrininthecaseofinflammation
AT ompanasenko ironbindingpropertyoflactoferrininthecaseofinflammation
AT sncherenkevich ironbindingpropertyoflactoferrininthecaseofinflammation