Klebsiella pneumoniae K2 producer of pyogenic liver abscess associated with biliary communication
Introduction: Hypervirulent strains of Klebsiella pneumoniae have gained clinical and epidemiological interest because of their capacity to cause severe and life-threatening infections. Methodology: We report a case involving infection with a hypervirulent K. pneumoniae K2 strain that caused liv...
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The Journal of Infection in Developing Countries
2022-09-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/15914 |
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| author | Daniel Aguilar-Zapata Josefina Duran-Bedolla Luis Esaú López-Jácome Humberto Barrios-Camacho Ulises Garza-Ramos Rafael Valdez-Vázquez |
| author_facet | Daniel Aguilar-Zapata Josefina Duran-Bedolla Luis Esaú López-Jácome Humberto Barrios-Camacho Ulises Garza-Ramos Rafael Valdez-Vázquez |
| author_sort | Daniel Aguilar-Zapata |
| collection | DOAJ |
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Introduction: Hypervirulent strains of Klebsiella pneumoniae have gained clinical and epidemiological interest because of their capacity to cause severe and life-threatening infections.
Methodology: We report a case involving infection with a hypervirulent K. pneumoniae K2 strain that caused liver abscess in a young woman with type 1 diabetes in Mexico.
Results: The infection was found to be associated with biliary tract communication. The virulence factors and capsular serotypes were identified by polymerase chain reaction analysis. After guided drainage and directed antibiotic treatment, the infection resolved and the patient recovered. Colonization of the gastrointestinal tract by hypervirulent K. pneumoniae strains, together with the presence of comorbidity, such as diabetes are important factors that contribute to the development of liver abscess.
Conclusions: The identification of virulent clones is important to understand the pathogenicity and improve control of infections in the patients.
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| format | Article |
| id | doaj-art-ddaa5683d7154ef7b6420e6477579ab9 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2022-09-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-ddaa5683d7154ef7b6420e6477579ab92025-08-20T02:14:20ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802022-09-01160910.3855/jidc.15914Klebsiella pneumoniae K2 producer of pyogenic liver abscess associated with biliary communicationDaniel Aguilar-Zapata0Josefina Duran-Bedolla1Luis Esaú López-Jácome2Humberto Barrios-Camacho3Ulises Garza-Ramos4Rafael Valdez-Vázquez5Infectología y Epidemiología hospitalaria. Fundación Clínica Médica Sur, Ciudad de México. MéxicoInstituto Nacional de Salud Pública (INSP), Centro de Investigación Sobre Enfermedades Infecciosas (CISEI), Laboratorio de Resistencia Bacteriana. Cuernavaca, Morelos, MéxicoLaboratorio de Infectología. Instituto Nacional de Rehabilitación, Ciudad de México. MéxicoInstituto Nacional de Salud Pública (INSP), Centro de Investigación Sobre Enfermedades Infecciosas (CISEI), Laboratorio de Resistencia Bacteriana. Cuernavaca, Morelos, MéxicoInstituto Nacional de Salud Pública (INSP), Centro de Investigación Sobre Enfermedades Infecciosas (CISEI), Laboratorio de Resistencia Bacteriana. Cuernavaca, Morelos, MéxicoInfectología y Epidemiología hospitalaria. Fundación Clínica Médica Sur, Ciudad de México. México Introduction: Hypervirulent strains of Klebsiella pneumoniae have gained clinical and epidemiological interest because of their capacity to cause severe and life-threatening infections. Methodology: We report a case involving infection with a hypervirulent K. pneumoniae K2 strain that caused liver abscess in a young woman with type 1 diabetes in Mexico. Results: The infection was found to be associated with biliary tract communication. The virulence factors and capsular serotypes were identified by polymerase chain reaction analysis. After guided drainage and directed antibiotic treatment, the infection resolved and the patient recovered. Colonization of the gastrointestinal tract by hypervirulent K. pneumoniae strains, together with the presence of comorbidity, such as diabetes are important factors that contribute to the development of liver abscess. Conclusions: The identification of virulent clones is important to understand the pathogenicity and improve control of infections in the patients. https://jidc.org/index.php/journal/article/view/15914infectioncolonizationKlebsiellaabscessvirulenceK2 |
| spellingShingle | Daniel Aguilar-Zapata Josefina Duran-Bedolla Luis Esaú López-Jácome Humberto Barrios-Camacho Ulises Garza-Ramos Rafael Valdez-Vázquez Klebsiella pneumoniae K2 producer of pyogenic liver abscess associated with biliary communication Journal of Infection in Developing Countries infection colonization Klebsiella abscess virulence K2 |
| title | Klebsiella pneumoniae K2 producer of pyogenic liver abscess associated with biliary communication |
| title_full | Klebsiella pneumoniae K2 producer of pyogenic liver abscess associated with biliary communication |
| title_fullStr | Klebsiella pneumoniae K2 producer of pyogenic liver abscess associated with biliary communication |
| title_full_unstemmed | Klebsiella pneumoniae K2 producer of pyogenic liver abscess associated with biliary communication |
| title_short | Klebsiella pneumoniae K2 producer of pyogenic liver abscess associated with biliary communication |
| title_sort | klebsiella pneumoniae k2 producer of pyogenic liver abscess associated with biliary communication |
| topic | infection colonization Klebsiella abscess virulence K2 |
| url | https://jidc.org/index.php/journal/article/view/15914 |
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