Investigating possible shared single nucleotide polymorphisms in isolated oral cleft and non-cleft facial morphology

Investigating possible shared single nucleotide polymorphisms in isolated oral cleft and non-cleft facial morphology

IntroductionFacial morphogenesis is regulated by several cellular interactions that are mediated by numerous morphogenetic signals. Based on the existing evidence, we hypothesize that oral cleft-associated single nucleotide polymorphisms (SNPs) are involved in the normal range of human face developm...

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Main Authors: Erika Calvano Küchler, Michelle Nascimento Meger, Bruna Correia Rauta Pires, Svenja Beisel-Memmert, Daniel Hemming, Ricardo D. Coletta, Rafaela Scariot, Mírian Aiko Nakane Matsumoto, Maria Angelica Hueb de Menezes Oliveira, Christian Kirschneck, Bianca Cavalcante-Leão
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Dental Medicine
Subjects:
face
genes
polymorphism
cleft lip and/or palate
craniofacial development
Online Access:https://www.frontiersin.org/articles/10.3389/fdmed.2025.1546295/full
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