Pharmacologically targeting Schwann cells to improve regeneration following nerve damage

Pharmacologically targeting Schwann cells to improve regeneration following nerve damage

Schwann cells provide essential support for nerve growth and survival following peripheral nerve damage by producing various growth factors and other signalling molecules. Modulating the proliferation, differentiation, migration, or myelination of Schwann cells could result in accelerated repair and...

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Bibliographic Details
Main Authors: Alaa A. Alhamdi, Shona Mackie, Ryan P. Trueman, Melissa L. D. Rayner
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
nerve regeneration
Schwann cells
signalling pathway
pharmacological intervention
cell phenotype
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1603752/full
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