Improved pharmacotherapy after revised dosing regimens of two slow-release formulations of benzylpenicillin in an Actinobacillus pleuropneumoniae infection model in pigs

Improved pharmacotherapy after revised dosing regimens of two slow-release formulations of benzylpenicillin in an Actinobacillus pleuropneumoniae infection model in pigs

Abstract Background Actinobacillus pleuropneumoniae (APP) is a Gram-negative bacterium that causes respiratory disease in pigs, resulting in significant economic losses and reduced animal welfare. In Sweden, the drug of choice for treatment of APP infections is benzylpenicillin. However, limited pha...

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Bibliographic Details
Main Authors: Marie Sjölund, Thomas Rosendal, Per Wallgren, Märit Pringle, Ulf Bondesson, Björn Bengtsson, Carl Ekstrand
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Acta Veterinaria Scandinavica
Subjects:
Antibiotic
Antimicrobial treatment
Pharmacokinetics
Pleuropneumonia
Porcine
Respiratory disease
Online Access:https://doi.org/10.1186/s13028-025-00806-9
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https://doi.org/10.1186/s13028-025-00806-9

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