A higher ratio of IL-2/IL-4 may be an early predictor of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

A higher ratio of IL-2/IL-4 may be an early predictor of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

ObjectivesTo investigate the correlation between cytokines at different time points after allogeneic hematopoietic stem cell transplantation (allo-HSCT) and the onset, severity, and therapeutic efficacy of acute graft-versus-host disease (aGVHD).MethodsWe performed a retrospective analysis of patien...

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Bibliographic Details
Main Authors: Yu Fu, Meifang Zhao, Xiaoliang Liu, Sujun Gao, Yehui Tan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
allogeneic hematopoietic stem cell transplantation
acute graft-versus-host disease
cytokines
diagnosis
therapeutic efficacy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1620761/full
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