Comparative Analysis of Gut Microbiota Between Wild and Captive Guizhou Snub‐Nosed Monkey (Rhinopithecus brelichi)

ABSTRACT Maintaining a healthy status is crucial for the successful captive breeding of critically endangered Rhinopithecus brelichi, it is conducive to ex situ conservation of this species and rejuvenation of its population. However, changes in the feeding environment and food can affect the compos...

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Main Authors: Xiaolong Huang, Haibo Li, Lan Zhang, Xu Zhang, Shaochuan Cheng, Yuying Yan, Wei Yang, Bingshun Meng, Zuobo Wang, Juanjuan Zhao, Jingcheng Ran
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Ecology and Evolution
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Online Access:https://doi.org/10.1002/ece3.70690
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author Xiaolong Huang
Haibo Li
Lan Zhang
Xu Zhang
Shaochuan Cheng
Yuying Yan
Wei Yang
Bingshun Meng
Zuobo Wang
Juanjuan Zhao
Jingcheng Ran
author_facet Xiaolong Huang
Haibo Li
Lan Zhang
Xu Zhang
Shaochuan Cheng
Yuying Yan
Wei Yang
Bingshun Meng
Zuobo Wang
Juanjuan Zhao
Jingcheng Ran
author_sort Xiaolong Huang
collection DOAJ
description ABSTRACT Maintaining a healthy status is crucial for the successful captive breeding of critically endangered Rhinopithecus brelichi, it is conducive to ex situ conservation of this species and rejuvenation of its population. However, changes in the feeding environment and food can affect the composition and function of the gut microbiota in R. brelichi, ultimately impacting its health and adaptation. Herein, 16S rRNA gene sequencing was employed to determine the gut microbiota composition and functional variations between wild and captive R. brelichi populations. The results showed that the captive group had higher alpha diversity than the wild group, and significant differences were observed in their beta diversity. Captive and wild R. brelichi showed similar microbiota at the phylum level, which mainly comprised Firmicutes, Bacteroidota, and Spirochaetota, but captivity reduced the Firmicutes/Bacteroides ratio. Differential abundance analysis revealed that the relative abundance of microbiota related to cellulose degradation, such as Prevotellaceae_UCG_001, Christensenellaceae_R_7_group, Ruminococcus, and Fibrobacter, differed significantly between the two groups. Furthermore, the potential pathogens Acinetobacter and Treponema were significantly abundant in wild and captive groups, respectively. Functional predictions demonstrated that the most significant functional pathways at the second level between captive and wild monkeys were carbohydrate, amino acid, and lipid metabolisms. The captive monkeys exhibited higher digestive capacity and endocrine regulation as well as a higher risk of infectious diseases than wild monkeys. These findings can serve as a valuable theoretical basis for promoting the healthy breeding of R. brelichi and as a guide for future evaluation of the health of wild and captive monkeys.
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spelling doaj-art-dda32cc91d1a4c668183af87fec9f6972025-08-20T02:56:02ZengWileyEcology and Evolution2045-77582024-12-011412n/an/a10.1002/ece3.70690Comparative Analysis of Gut Microbiota Between Wild and Captive Guizhou Snub‐Nosed Monkey (Rhinopithecus brelichi)Xiaolong Huang0Haibo Li1Lan Zhang2Xu Zhang3Shaochuan Cheng4Yuying Yan5Wei Yang6Bingshun Meng7Zuobo Wang8Juanjuan Zhao9Jingcheng Ran10Guizhou Academy of Forestry Guiyang ChinaGuizhou Fanjingshan Forest Ecosystem Observation and Research Station Tongren ChinaGuizhou Academy of Forestry Guiyang ChinaGuizhou Academy of Forestry Guiyang ChinaGuizhou Academy of Forestry Guiyang ChinaGuizhou Academy of Forestry Guiyang ChinaGuizhou Fanjingshan Forest Ecosystem Observation and Research Station Tongren ChinaGuizhou Academy of Forestry Guiyang ChinaGuizhou Academy of Forestry Guiyang ChinaGuizhou Academy of Forestry Guiyang ChinaGuizhou Academy of Forestry Guiyang ChinaABSTRACT Maintaining a healthy status is crucial for the successful captive breeding of critically endangered Rhinopithecus brelichi, it is conducive to ex situ conservation of this species and rejuvenation of its population. However, changes in the feeding environment and food can affect the composition and function of the gut microbiota in R. brelichi, ultimately impacting its health and adaptation. Herein, 16S rRNA gene sequencing was employed to determine the gut microbiota composition and functional variations between wild and captive R. brelichi populations. The results showed that the captive group had higher alpha diversity than the wild group, and significant differences were observed in their beta diversity. Captive and wild R. brelichi showed similar microbiota at the phylum level, which mainly comprised Firmicutes, Bacteroidota, and Spirochaetota, but captivity reduced the Firmicutes/Bacteroides ratio. Differential abundance analysis revealed that the relative abundance of microbiota related to cellulose degradation, such as Prevotellaceae_UCG_001, Christensenellaceae_R_7_group, Ruminococcus, and Fibrobacter, differed significantly between the two groups. Furthermore, the potential pathogens Acinetobacter and Treponema were significantly abundant in wild and captive groups, respectively. Functional predictions demonstrated that the most significant functional pathways at the second level between captive and wild monkeys were carbohydrate, amino acid, and lipid metabolisms. The captive monkeys exhibited higher digestive capacity and endocrine regulation as well as a higher risk of infectious diseases than wild monkeys. These findings can serve as a valuable theoretical basis for promoting the healthy breeding of R. brelichi and as a guide for future evaluation of the health of wild and captive monkeys.https://doi.org/10.1002/ece3.7069016S rRNA gene sequencinggut microbiotaRhinopithecus brelichiwild and captive
spellingShingle Xiaolong Huang
Haibo Li
Lan Zhang
Xu Zhang
Shaochuan Cheng
Yuying Yan
Wei Yang
Bingshun Meng
Zuobo Wang
Juanjuan Zhao
Jingcheng Ran
Comparative Analysis of Gut Microbiota Between Wild and Captive Guizhou Snub‐Nosed Monkey (Rhinopithecus brelichi)
Ecology and Evolution
16S rRNA gene sequencing
gut microbiota
Rhinopithecus brelichi
wild and captive
title Comparative Analysis of Gut Microbiota Between Wild and Captive Guizhou Snub‐Nosed Monkey (Rhinopithecus brelichi)
title_full Comparative Analysis of Gut Microbiota Between Wild and Captive Guizhou Snub‐Nosed Monkey (Rhinopithecus brelichi)
title_fullStr Comparative Analysis of Gut Microbiota Between Wild and Captive Guizhou Snub‐Nosed Monkey (Rhinopithecus brelichi)
title_full_unstemmed Comparative Analysis of Gut Microbiota Between Wild and Captive Guizhou Snub‐Nosed Monkey (Rhinopithecus brelichi)
title_short Comparative Analysis of Gut Microbiota Between Wild and Captive Guizhou Snub‐Nosed Monkey (Rhinopithecus brelichi)
title_sort comparative analysis of gut microbiota between wild and captive guizhou snub nosed monkey rhinopithecus brelichi
topic 16S rRNA gene sequencing
gut microbiota
Rhinopithecus brelichi
wild and captive
url https://doi.org/10.1002/ece3.70690
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