Prospective multicentre accuracy evaluation of the FUJIFILM SILVAMP TB LAM test for the diagnosis of tuberculosis in people living with HIV demonstrates lot-to-lot variability.

Prospective multicentre accuracy evaluation of the FUJIFILM SILVAMP TB LAM test for the diagnosis of tuberculosis in people living with HIV demonstrates lot-to-lot variability.

There is an urgent need for rapid, non-sputum point-of-care diagnostics to detect tuberculosis. This prospective trial in seven high tuberculosis burden countries evaluated the diagnostic accuracy of the point-of-care urine-based lipoarabinomannan assay FUJIFILM SILVAMP TB LAM (FujiLAM) among inpati...

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Main Authors: Rita Székely, Bianca Sossen, Madalo Mukoka, Monde Muyoyeta, Elizabeth Nakabugo, Jerry Hella, Hung Van Nguyen, Sasiwimol Ubolyam, Kinuyo Chikamatsu, Aurélien Macé, Marcia Vermeulen, Chad M Centner, Sarah Nyangu, Nsala Sanjase, Mohamed Sasamalo, Huong Thi Dinh, The Anh Ngo, Weerawat Manosuthi, Supunnee Jirajariyavej, Satoshi Mitarai, Nhung Viet Nguyen, Anchalee Avihingsanon, Klaus Reither, Lydia Nakiyingi, Andrew D Kerkhoff, Peter MacPherson, Graeme Meintjes, Claudia M Denkinger, Morten Ruhwald, FujiLAM Study Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0303846&type=printable
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