Temporal, Spatial and Tissue-Specific Expression of a Myogenin-lacZ Transgene Targeted to the Hprt Locus in Mice

A lacZ transgene, expressed by the myogenin promoter, was introduced into the mouse hypoxanthine phosphoribosyltransferase (Hprt) locus by gene targeting in embryonic stem cells. Embryos between E10.5—E18.5 days were analyzed for expression of the transgene after staining for β-galactosidase activit...

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Bibliographic Details
Main Authors: Jay L. Vivian, William H. Klein, Paul Hasty
Format: Article
Language:English
Published: Taylor & Francis Group 1999-07-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/99271rr04
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